5343-54-4

Usage

Uses

Used in Chemical Production:
2,2-DIMETHYLDECANOIC ACID is used as a key component in the production of various chemicals, contributing to the synthesis of a wide range of products.
Used in Pharmaceutical Industry:
2,2-DIMETHYLDECANOIC ACID is used as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new medications.
Used in Plasticizer Synthesis:
2,2-DIMETHYLDECANOIC ACID is used as an intermediate in the production of plasticizers, which are additives that increase the flexibility and workability of plastics.
Used in Lubricant Production:
2,2-DIMETHYLDECANOIC ACID is used as a component in the formulation of lubricants, enhancing their performance and reducing friction in various applications.
Used in Surfactant Manufacturing:
2,2-DIMETHYLDECANOIC ACID is used in the production of surfactants, which are compounds that reduce the surface tension of a liquid, making it useful in cleaning and stabilization processes.

InChI:InChI=1/C12H24O2/c1-4-5-6-7-8-9-10-12(2,3)11(13)14/h4-10H2,1-3H3,(H,13,14)

Upstream product

• 108753-59-9 isobutyric acid-(1,1-diethyl-propyl ester) 
• 855756-24-0 2,2-dimethyl-decanoic acid amide 
• 61415-93-8 2,2-dimethyldecanenitrile 
• 111-83-1 1-bromo-octane 
• 79-31-2 isobutyric Acid 
• 74-83-9 methyl bromide 
• 24323-23-7 2-methyl decanoic acid 

Downstream Products

• 140112-69-2 2,2-Dimethyl-decanoic acid (2,4,6-trimethoxy-phenyl)-amide 
• 117815-03-9 4,4-dimethyl-2-[2-methyldecan-2-yl]-4,5-dihydrooxazole 

Relevant academic research and scientific papers

CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF

The present application discloses a compound of formula (I) or a salt thereof: (I) and compositions comprising such compound or salt thereof. The use of such compound, salt thereof or composition comprising same for treating anemia or leukopenia, fibrosis, cancer, hypertension and/or a metabolic condition in a subject is also disclosed.

PhSO2SCF2H: A Shelf-Stable, Easily Scalable Reagent for Radical Difluoromethylthiolation

A new shelf-stable and easily scalable difluoromethylthiolating reagent S-(difluoromethyl) benzenesulfonothioate (PhSO2SCF2H) was developed. PhSO2SCF2H is a powerful reagent for radical difluoromethylthiolation of aryl and alkyl boronic acids, decarboxylative difluoromethylthiolation of aliphatic acids, and a phenylsulfonyl-difluoromethylthio difunctionalization of alkenes under mild reaction conditions.

Inhibitors of Acyl-CoA:cholesterol acyltransferase. I. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents

A series of fatty acid anilides was prepared, and compounds were tested for their ability to inhibit the enzyme acyl-CoA:cholesterol acyltransferase (ACAT) in vitro and to lower plasma total cholesterol and elevate high- density lipoprotein cholesterol in cholesterol-fed rats in vivo. The compounds reported were found to fall into two subclasses with different anilide SAR. For nonbranched acyl analogues, inhibitory potency was found to be optimal with bulky 2,6-dialkyl substitution. For α-substituted acyl analogues, there was little dependence of in vitro potency on anilide substitution and 2,4,6-trimethoxy was uniquely preferred. Most of the potent inhibitors (IC50 50 nM) were found to produce significant reductions in plasma total cholesterol in cholesterol-fed rats. Additionally, in vivo activity could be improved significantly by the introduction of α,α- disubstitution into the fatty acid portion of the molecule. A narrow group of α,α-disubstituted trimethoxyanilides, exemplified by 2,2-dimethyl-N-(2,4,6- trimethoxyphenyl)dodecanamide (39), was found to not only lower plasma total cholesterol (-60%) in cholesterol-fed rats but also elevate levels of high- density lipoprotein cholesterol (+94%) in this model at the screening dose of 0.05% in the diet (ca. 50 mg/kg).