53442-24-3

Basic information

• Product Name: 2-Amino-6-phenylphenol
• Synonyms: 2-Amino-6-phenylphenol;3-Amino-2-biphenylol
• CAS NO: 53442-24-3
• Molecular Formula: C₁₂H₁₁NO
• Molecular Weight: 185.22
• Mol File: 53442-24-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-6-phenylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-phenylphenol(53442-24-3)
• EPA Substance Registry System: 2-Amino-6-phenylphenol(53442-24-3)

Safety Data

• Hazardous Substances Data: 53442-24-3(Hazardous Substances Data)

Upstream product

• 833-50-1 2-phenylbenzo[d]oxazole 
• 107449-13-8 O-(2-biphenylyl)hydroxylamine 

Downstream Products

• 76524-98-6 2-methyl-7-phenyl-benzoxazole 
• 70995-06-1 7-phenyl-2-p-tolyl-benzooxazole 
• 1374772-49-2 6-(morpholin-4-yl)-2-[(7-phenyl-1,3-benzoxazol-2-yl)methyl]pyrimidin-4(3H)-one 
• 182499-66-7 N-[2-Hydroxy-3-phenylphenyl]-N'-[2,3-dichlorophenyl] urea 
• 52793-99-4 8-hydroxy-7-phenylquinoline 

Relevant articles and documents

Palladium-Catalyzed Regioselective C-H Bond Arylations of Benzoxazoles and Benzothiazoles at the C7 Position

We report herein, a very simple catalytic system for the direct arylation of benzoxazole and benzothiazole derivatives at C7 position, namely, phosphine-free PdCl2 associated with PivOK in NMP at 150 °C. (Thio)phenoxy chelation-assisted Pd-catalyzed C-H bond cleavage, from an opened intermediate, was proposed to explain this unique regioselectivity. This reaction allows the synthesis of 2-amino-6-arylphenols through the ring opening of the benzoxazole.