53448-97-8

Upstream product

• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 94-41-7 benzalacetophenone 
• 1083-30-3 dihydrochalcone 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 591-50-4 iodobenzene 
• 61637-11-4 (2E)-1-phenyl-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one 
• 23665-09-0 phenylzinc iodide 
• 3262-89-3 triphenylboroxine 
• 128796-45-2 2,4,6-tris-(4-trifluoromethylphenyl)boroxine 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 61637-11-4 3-(4-(trifluoromethyl)phenyl)-1-phenylprop-2-en-1-one 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

Enantioselective β-C(sp3)-H arylation of amides: Via synergistic nickel and photoredox catalysis

An enantioselective benzylic β-C(sp3)-H arylation of amides via synergistic nickel and photoredox catalysis is reported. The C-H bond is activated by a bromine-radical-mediated C-H cleavage. This mild yet straightforward protocol provides arylation products in up to 96% yield and with up to 95% ee. This journal is

Enantioselective Conjugate Addition of Stabilized Arylzinc Iodide to Enones: an Improved Protocol of the Hayashi Reaction

Stabilised arylzinc iodide, prepared by direct insertion of zinc into aryl iodides, were used as nucleophiles in the Hayashi Rh-catalysed enantioselective conjugate addition to enones. The reaction conditions were optimized in the addition of phenylzinc i

Asymmetric Conjugate Addition of Organoboron Reagents to Common Enones Using Copper Catalysts

Copper complexes of phosphoramidites efficiently catalyzed asymmetric addition of arylboron reagents to acyclic enones. Importantly, rare 1,4-insertion of arylcopper(I) was identified which led directly to O-bound copper enolates. The new mechanism is fundamentally different from classical oxidative addition/reductive elimination of organocopper(I) on enones.

Synthesis, Coordination Properties, and Catalytic Application of Triarylmethane-Monophosphines

A new class of triarylmethane-based phosphines (L1-L4) and their Pd(II) and Rh(I) complexes were synthesized and subsequently characterized by NMR spectroscopy and X-ray diffraction analysis. The reactions of these phosphines with [PdCl(π-allyl)]2 gave the square-planar Pd(II) complexes [PdCl(π-allyl)(L)] (L = L1-L4). The treatment of [PdCl(π-allyl)(L3)] and [PdCl(π-allyl)(L4)], which have CF3-substituted triarylmethane and 9-arylfluorene moieties, respectively, with LiOtBu afforded P,C(sp3)-chelated palladacycle complexes. Reversibility between a C(sp3)-M covalent bond and a C(sp3)-H···M interaction was experimentally demonstrated using [RhCl(nbd)]2 as a Rh(I) source. The triarylmethane-monophosphines L1-L4 were applied to the Pd-catalyzed 1,4-addition of arylboronic acids to enones.

Ligand-free nickel-catalysed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds

A simple and efficient ligand-free nickel-based catalytic system has been developed for the 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds. With catalyst loadings of 1-2 mol%, a series of 1,4-adducts from chalcones and cinnamates was obtained in moderate to excellent yields within 5-30 min under a nitrogen atmosphere and microwave irradiation. The 1,4-addition of arylboronic acids to acrylates is less efficient.

Triazolium salts as appropriate catalytic scaffolds for 1,4-additions to α,β-unsaturated carbonyls

1,2,3-Triazole derivatives containing a rigid dihydroanthracenyl skeleton are suitable precursors for both organometallic and organo-based catalysts. A Rh-carbene complex and the triazolium salt efficiently catalyzed the 1,4-additions of C- and heterodonor reagents to α,β-unsaturated carbonyl substrates, respectively. Copyright