5345-01-7

Basic information

• Product Name: 3-ETHYL-3-METHYLGLUTARIC ACID
• Synonyms: 3-ethyl-3-methylpentanedioic acid;3-ETHYL-3-METHYLGLUTARIC ACID 97%;Einecs 226-294-2;B-METHYL-B-ETHYLGLUTARIC ACID;BETA-ETHYL-BETA-METHYLGLUTARIC ACID;B-ETHYL-B-METHYLGLUTARIC ACID;3-ETHYL-3-METHYLGLUTARIC ACID
• CAS NO: 5345-01-7
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.19
• EINECS: 226-294-2
• Mol File: 5345-01-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 77-81 °C(lit.)
• Boiling Point: 345.17°C (rough estimate)
• Flash Point: 157.3°C
• Appearance: /
• Density: 1.3010 (rough estimate)
• Vapor Pressure: 0.000111mmHg at 25°C
• Refractive Index: 1.4362 (estimate)
• Water Solubility: very faint turbidity in Water
• CAS DataBase Reference: 3-ETHYL-3-METHYLGLUTARIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHYL-3-METHYLGLUTARIC ACID(5345-01-7)
• EPA Substance Registry System: 3-ETHYL-3-METHYLGLUTARIC ACID(5345-01-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 5345-01-7(Hazardous Substances Data)

Usage

General Description

3-Ethyl-3-methylglutaric acid is a chemical compound with the molecular formula C7H12O4. It is a derivative of glutaric acid and contains an ethyl and a methyl substitution on the third carbon of the chain. 3-ETHYL-3-METHYLGLUTARIC ACID is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a precursor in the production of flavors and fragrances. The compound has potential applications in the field of organic synthesis and chemical research.

InChI:InChI=1/C8H14O4/c1-3-8(2,4-6(9)10)5-7(11)12/h3-5H2,1-2H3,(H,9,10)(H,11,12)/p-2

Upstream product

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Downstream Products

• 50849-40-6 N,β-Dimethyl-β-ethyl-glutarimid 
• 102165-68-4 4-ethyl-1-[5-(4-amino-phenoxy)-pentyl]-4-methyl-piperidine-2,6-dione 
• 6970-57-6 3-ethyl-3-methylglutaric anhydride 
• 64-65-3 bemegride 
• 5338-98-7 3-ethyl-3-methyl-glutaric acid monomethyl ester 
• 1197-86-0 2-methyl-5-ethyl-5-methylcyclohexane-1,3-dione 
• 4045-31-2 4-ethyl-4-methylpiperidine 

Relevant articles and documents

1,1-Alkanediol dicarboxylate linked antibacterial agents

Useful antibacterial agents in which a penicillin and/or a beta-lactamase inhibitor are linked via 1,1-alkanediol dicarboxylates are of the formula STR1 where A is the residue of certain dicarboxyic acids, R3 is H or (C1 -C3), n is zero or 1 such that when n is zero R is P or B and R1 is the residue of certain esters, H or a salt thereof; and when n is 1, one of R and R1 is P and the other is B, and P is STR2 where R2 is H or certain acyl groups, and B is the residue of a beta-lactamase inhibiting carboxylic acid; a method for their use, pharmaceutical compositions thereof and intermediates useful in their production.

Geminate-Substituted Cyclopentadienes. 1. Synthesis of 5,5-Dialkylcyclopentadienes via 4,4-Dialkylcyclopent-2-en-1-ones.

A synthetic route for the preparation of 5,5,-dialkylcyclopentadienes (1) via 4,4-dialkylcyclopent-2-en-1-ones (3) is described.Beginnig with ketones (in which the two carbonyl substituents will become the two alkyl groups in the title compounds), the route traverses the Guareschi imides 5, 3,3-dialkylglutaric acids 4 and their ethyl esters 7, masked acyloins 8, cyclopentenones 3, alkohols 9, and bromides 10 to reach the dienes 1.Physical properties of five such derivates 1 and 3 (dimethyl, methylethyl,diethyl, methyl-n-propyl, and methylisopropyl) are presented.