53460-46-1

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

InChI:InChI=1/C10H19N/c1-9(2)4-8-5-10(3,6-9)7-11-8/h8,11H,4-7H2,1-3H3/p+1/t8-,10-/m1/s1

Upstream product

• 7027-11-4 isophoronenitrile 

Downstream Products

• 81811-07-6 6-Ethyl-1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane; hydriodide 
• 88502-86-7 6-chloroacetyl-1,3,3-trimethyl-6-azabicyclo<3.2.1>octane 
• 777081-72-8 [4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-phenyl]carbamic acid tert-butyl ester 
• 1173693-73-6 (6-(4-Methoxy-3,5-dimethylphenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone 
• 1178327-82-6 [5-bromo-thiophen-3-yl]-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]oct-6-yl)-methanone 

Relevant academic research and scientific papers

METHOD FOR THE PRODUCTION OF ISOPHORONDIAMINE (IPDA, 3-AMINOMETHYL-3,5,5-TRIMETHYLCYCLOHEXYLAMINE) HAVING A HIGH CIS/TRANS-ISOMER RATIO

The invention relates to a method for the production of 3 aminomethyl-3,5,5- trimethylcyclohexylamine (isophorondiamine, IPDA) which has a high cis/trans isomer ratio. IPDA having a cis/trans isomer ratio in the range of 63/37 - 66/34 can be obtained in a temperature-independent manner by reacting IPDA having any particular cis/trans isomer ratio with H2 and NH3 in the presence of a hydrogenating catalyst. IPDA having a cis/trans isomer ratio of at least 73/27, which is an important starting material for the synthesis of polyurethanes and polyamides, can be obtained by combining said isomerization method with distillation methods.

Tetracyclic benzimidazole derivatives and combinatorial libraries thereof

The present invention relates to novel tetracyclic benzimidazole derivative compounds of the following formula: wherein R1to R10have the meanings described in here. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing tetracyclic benzimidazole derivative compounds.