53473-06-6Relevant academic research and scientific papers
Substituent effects on the regioselectivity of enzymatic acylation of 6-O-alkylglycopyranosides using Pseudomonas cepacia lipase
MacManus,Vulfson
, p. 281 - 291 (1995)
The regioselectivity of acylation of a range of 6-O-protected glycosides using Pseudomonas cepacia lipase in vinyl acetate was tigated. In general, α-glycosides were acylated at the O-2 position and β-glycosides were acylated at the O-3 position. The effe
Synthesis of novel carbohydrate based pyridinium ionic liquids and cytotoxicity of ionic liquids for mammalian cells
Brietzke, Andreas,Eickner, Thomas,Jopp, Stefan,Kragl, Udo,Rei?, Melanie,Stein, Florian,Villinger, Alexander,Vogel, Christian
, p. 14299 - 14304 (2020/04/23)
The large pool of naturally occurring carbohydrates with their diversity in chirality and structure led to the idea of a systematic investigation of carbohydrate based ILs. To this end, we investigated the influence of different ether groups, mainly methyl or ethyl ether, on the secondary OH groups as well as different configurations on physical properties such as melting point, thermostability and especially the influence on cell toxicity. For this investigation we chose α- and β-methyl-, β-allyl- and β-phenyl d-glucopyranose as well as four 1-deoxy-pentoses. In order to be able to classify the results, more ionic liquids with different structural motives were examined for cytotoxicity. Here, we present data that confirm the biocompatibility of such ILs consisting of naturally occurring molecules or their derivatives. The synthesized carbohydrate based ILs were tested for their suitability as additives in coatings for medical applications such as drug-eluting balloons.
