Substituent effects on the regioselectivity of enzymatic acylation of 6-O-alkylglycopyranosides using Pseudomonas cepacia lipase

Article abstract of DOI:10.1016/0008-6215(95)00292-8

The regioselectivity of acylation of a range of 6-O-protected glycosides using Pseudomonas cepacia lipase in vinyl acetate was tigated. In general, α-glycosides were acylated at the O-2 position and β-glycosides were acylated at the O-3 position. The effe