53484-76-7

Basic information

• Product Name: 4-Phenyl-4-piperidine carboxylic acid HCl
• Synonyms: 4-Phenyl-4-piperidine Carboxylic Acid Hydrochloric Acid Salt
• CAS NO: 53484-76-7
• Molecular Formula: C₁₂H₁₅NO₂*ClH
• Molecular Weight: 241.71394
• Mol File: 53484-76-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Phenyl-4-piperidine carboxylic acid HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-4-piperidine carboxylic acid HCl(53484-76-7)
• EPA Substance Registry System: 4-Phenyl-4-piperidine carboxylic acid HCl(53484-76-7)

Safety Data

• Hazardous Substances Data: 53484-76-7(Hazardous Substances Data)

Usage

General Description

4-Phenyl-4-piperidine carboxylic acid HCl is a chemical compound that consists of a piperidine ring with a phenyl group and a carboxylic acid moiety attached to it. The compound is usually found in the form of a hydrochloride salt, denoted by the HCl in its name. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The presence of the piperidine ring makes this compound a potential candidate for drug design and development due to its pharmacological properties. Additionally, the presence of the carboxylic acid group makes it useful for chemical reactions and as a building block in organic synthesis.

Upstream product

• 51304-58-6 4-cyano-4-phenylpiperidine hydrochloride 

Downstream Products

• 1279882-69-7 1-{[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]carbonyl}-4-phenylpiperidine-4-carboxylic acid 
• 1365037-07-5 1-{[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]carbonyl}-4-phenylpiperidine-4-carboxamide 
• 83898-15-1 4-phenyl-piperidine-4-carboxylic acid methyl ester; hydrochloride 
• 167262-68-2 N-(t-butyloxycarbonyl)-4-phenylpiperidine-4-carboxylic acid 

Relevant articles and documents

NOVEL HETEROCYCLIC SUBSTITUTED PYRROLIDINE AMIDE DERIVATIVES

The present invention relates to novel heterocyclic substituted pyrrolidine amide derivatives of formula (1), and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.

SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES

The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.