5349-80-4 Usage
Uses
Used in Chemical Synthesis:
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE is used as an intermediate in the synthesis of various organic compounds for [application reason] its ability to form complexes with metal ions, making it a versatile building block in chemical reactions.
Used in Pharmaceutical Industry:
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE is used as a starting material for the development of new drugs for [application reason] its potential to chelate metal ions, which can be beneficial in the treatment of metal-related disorders or as a component in drug design.
Used in Analytical Chemistry:
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE is used as a reagent in analytical chemistry for [application reason] its ability to form stable complexes with metal ions, which can be utilized in the detection and quantification of metal ions in various samples.
Used in Environmental Applications:
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE is used in environmental applications for [application reason] its potential to sequester metal ions, which can be useful in the remediation of contaminated water or soil samples.
Used in Material Science:
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE is used in the development of new materials for [application reason] its ability to form complexes with metal ions, which can be exploited in the creation of novel metal-organic frameworks or other advanced materials with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 5349-80-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,4 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5349-80:
(6*5)+(5*3)+(4*4)+(3*9)+(2*8)+(1*0)=104
104 % 10 = 4
So 5349-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2O/c1-14(2)9-10-6-4-5-7-11(10)12(16-14)8-13(17)15-3/h4-8,16H,9H2,1-3H3,(H,15,17)/b12-8-
5349-80-4Relevant academic research and scientific papers
Metal-catalyzed hydroxylaminolysis of unactivated amide and peptide bonds.
Gomez-Reyes, Baldomero,Yatsimirsky, Anatoly K
, p. 866 - 872 (2007/10/03)
Kinetics of the hydroxylaminolysis of acetamide, glycinamide, glycylglycine and triglycine have been studied in the range of temperatures 37-60 degrees C as a function of pH and hydroxylamine concentration. Rate constants for specific acid, general-acid and general-base catalyzed pathways have been determined for all substrates (for glycine derivatives rate constants for different protonation forms were obtained). Testing different metal ions as possible reaction catalysts revealed a significant catalytic effect of Zn(II) on the hydroxylaminolysis of glycine substrates, but not acetamide. On the basis of the kinetic results, a mechanism of Zn(II) catalysis is proposed, which involves the coordination of the metal ion to the alpha-amino group of the substrate and the base-assisted nucleophilic attack of hydroxylamine on the bound substrate. The product analysis by proton NMR shows that the primary reaction product in the catalytic reaction is glycine hydroxamic acid, which undergoes further Zn(II)-catalyzed hydrolysis to glycine. Thus the final result of the Zn(II)-catalyzed treatment of peptides by hydroxylamine is hydrolytic cleavage.
