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Glycyladenylate, also known as glycine adenosine monophosphate (GAMP), is a purine ribonucleoside 5'-monophosphate derived from adenosine 5'-monophosphate (AMP). In this molecule, one of the hydroxy groups of the phosphate has been condensed with the carboxylic acid group of glycine, resulting in a unique structure with potential applications in various fields.

35985-26-3

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35985-26-3 Usage

Uses

Used in Pharmaceutical Industry:
Glycyladenylate is used as an intermediate in the synthesis of various nucleotides and nucleic acid analogs for the development of new drugs targeting different diseases. Its unique structure allows for the creation of modified nucleotides that can be used in the design of novel therapeutic agents.
Used in Research and Development:
Glycyladenylate serves as a valuable compound in the field of molecular biology and biochemistry. It is used as a research tool to study the mechanisms of nucleotide synthesis, enzyme activity, and the role of nucleotides in cellular processes. This knowledge can be applied to develop new strategies for treating various diseases and understanding the fundamental aspects of cellular function.
Used in Diagnostic Applications:
Due to its specific interaction with certain enzymes and receptors, glycyladenylate can be employed in the development of diagnostic tools and assays. These tools can help in the detection and monitoring of diseases related to nucleotide metabolism and other related pathways.

Check Digit Verification of cas no

The CAS Registry Mumber 35985-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,8 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 35985-26:
(7*3)+(6*5)+(5*9)+(4*8)+(3*5)+(2*2)+(1*6)=153
153 % 10 = 3
So 35985-26-3 is a valid CAS Registry Number.

35985-26-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name glycyl-AMP

1.2 Other means of identification

Product number -
Other names [5']Adenylsaeure-glycin-anhydrid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35985-26-3 SDS

35985-26-3Relevant academic research and scientific papers

Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide

Leman, Luke J.,Orgel, Leslie E.,Ghadiri, M. Reza

, p. 20 - 21 (2007/10/03)

Carbonyl sulfide (COS), a component of volcanic gas emissions and interstellar gas clouds, is shown to be an efficient condensing agent in the context of phosphate chemistry in aqueous solutions. We report that high-energy aminoacyl-phosphate anhydrides a

31P NMR study on aminoacylatiqn of 5′-AMP and its analogs

Moriguchi, Tomohisa,Yanagi, Terukazu,Wada, Takeshi,Sekine, Mitsuo

, p. 1859 - 1865 (2007/10/03)

The progress of aminoacylation of 5′-AMP with amino acids in the presence of several condensing reagents was monitored by 31P NMR. The resulting products were identified on the basis of their 31P NMR chemical shifts. The aminoacylati

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