5350-86-7

Usage

Uses

Used in Pharmaceutical Industry:
2,3-diphenylbutanoic acid serves as a chiral auxiliary, playing a crucial role in the synthesis of an array of drugs and intermediates. Its stereoselective properties are instrumental in the production of enantiomerically pure compounds, which is vital for ensuring the desired therapeutic effects and minimizing potential side effects of medications.
Used in Organic Chemistry:
As a reagent, 2,3-diphenylbutanoic acid contributes to various organic chemical reactions, facilitating the synthesis of complex organic molecules and aiding in the development of new chemical entities with potential applications in different fields.
Used in Chiral Separation Techniques:
2,3-diphenylbutanoic acid is utilized in chiral separation techniques, which are essential for distinguishing between enantiomers of chiral compounds. This ability to differentiate between mirror-image molecules is critical in pharmaceuticals, where the biological activity of enantiomers can significantly vary.
Used in Research for Anti-inflammatory and Analgesic Properties:
2,3-diphenylbutanoic acid has been the subject of research for its potential as an anti-inflammatory and analgesic agent. These properties could lead to the development of new treatments for conditions characterized by pain and inflammation, offering patients improved therapeutic options.

Upstream product

• 600-30-6 erythro-2,3-dibromobutanoic acid 
• 71-43-2 benzene 
• 103-82-2 phenylacetic acid 
• 6749-54-8 1-phenylethyl p-toluenesulfonate 
• 4553-07-5 ethyl phenylcyanoacetate 
• 103385-15-5 (±)-2,3-diphenylbutanoic acid 
• 585-71-7 (1-bromoethyl)benzne 
• 672-65-1 (1-chloroethyl)benzene 
• 16537-09-0 t-butyl phenylacetate 
• 917-64-6 methyl magnesium iodide 
• 2510-95-4 2,3-diphenylacrylonitrile 
• 5558-38-3 (+/-)-(2S,3R)-2,3-diphenylbutanenitrile 
• 5558-90-7 (Z)-2,3-diphenylpropanenitrile 
• 34317-82-3 (Z)-2,3-diphenyl-2-butenoic acid 

Downstream Products

• 108774-24-9 (2S*,3R*)-2,3-diphenylbutan-1-ol 
• 16213-71-1 (+/-)-erythro-2.3-diphenyl-butyric acid amide 
• 108774-24-9 2,3-diphenylbutan-1-ol 
• 16213-71-1 (+/-)-threo-2.3-diphenyl-butyric acid amide 
• 101746-98-9 (+/-)-methanesulfonic acid-(threo-2,3-diphenyl-butyl ester) 
• 90020-71-6 (+/-)-threo-3,4-diphenyl-valeric acid 
• 101746-98-9 (+/-)-methanesulfonic acid-(erythro-2,3-diphenyl-butyl ester) 
• 90020-71-6 (+/-)-erythro-3,4-diphenyl-valeric acid 
• 72946-98-6 (+/-)-trans-4-Oxo-1-methyl-2-phenyl-tetralin 
• 109394-57-2 (+/-)-erythro-3,4-diphenyl-valeronitrile 
• 51760-87-3 (+/-)-erythro-2,3-diphenyl-butyryl chloride 

Relevant academic research and scientific papers

GUANIDINE DERIVATIVES AS TRPC MODULATORS

The present invention is directed to guanidine derivatives as inhibitors of transient receptor potential canonical channels (TRPC channels), in particular TRPC3 and/or TRPC6 and/or TRPC7 activity, more particularly TRPC6 activity. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders mediated by TRPC channels (Formula (I))

Regioselective alkylation of lithium dienediolates of α,β- unsaturated carboxylic acids

Lithium carboxylic acids dienediolates are regioselectively alkylated at the α-carbon by reaction with tosylates derived from both primary and secondary alcohols. Both regio- and diastereoselectivity are improved when compared with those obtained in the c

Lithium enediolates and dienediolates of carboxylic acids in synthesis: Alkylation with secondary halides

High yields in the alkylation of dianions of α,β-unsaturated carboxylic acids with secondary halides can be obtained despite elimination reactions occurring. α-Regioselectivity for the alkylation of but-2-enoic acids (1-4) is seldom obtained. Although dou

CATALYTIC ASYMMETRIC HYDROGENATION OF β-DISUBSTITUTED α-PHENYLACRYLIC ACIDS. ASYMMETRIC SYNTHESIS OF CARBOXYLIC ACIDS CONTAINING TWO VICINAL CHIRAL CARBON CENTERS

Hydrogenation of trisubstituted acrylic acids ((E)- and (Z)-MeC(R)=CPhCOOH: R = CD3, Et, Ph) in the presence of a chiral (aminoalkyl)ferrocenylphosphine-rhodium catalyst installed asymmetric configurations at two vicinal carbons at once giving optically a