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1-Phenylethyl p-toluenesulfonate, also known as phenethyl p-toluenesulfonate or PPTS, is an organic compound with the chemical formula C15H16O3S. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents such as ethanol, acetone, and dichloromethane. PPTS is commonly used as an acid catalyst in organic synthesis, particularly in the dehydration of alcohols to form alkenes, and as a reagent in the protection of alcohols. It is also employed in the preparation of various pharmaceuticals and agrochemicals. Due to its reactivity and stability, PPTS is a valuable tool in the field of organic chemistry, facilitating a range of chemical transformations.

6749-54-8

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6749-54-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6749-54-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,4 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6749-54:
(6*6)+(5*7)+(4*4)+(3*9)+(2*5)+(1*4)=128
128 % 10 = 8
So 6749-54-8 is a valid CAS Registry Number.

6749-54-8Relevant academic research and scientific papers

Reaction of Hydrazones with Methoxy(tosyloxy)iodobenzene (MTIB): Tosylate Formation under Oxidative Conditions

Ramsden, Christopher A.,Rose, Helen L.

, p. 27 - 28 (2007/10/03)

Treatment of aromatic hydrazones 1 containing electron-withdrawing, reduction sensitive substituents with MTIB gives the corresponding tosylates 2 in high yield. When the tosylate is particularly reactive the thermodynamically more stable methyl ether 3 is isolated. Analogous reactions with DAIB give acetates 4 in high yield. Dialkyl hydrazones give olefinic products (e.g. 7 and 8). (+)-Camphor hydrazone 1k with either MTIB or DAIB gives both camphene 12 (major product) and tricyclene 11 (minor product) suggesting that a carbene pathway accounts for some of the material formed in these oxidations.

Nucleophilic Substitiution Reactions of 1-Phenylethyl Benzenesulfonates with Anilines in Methanol-Acetonitrile

Lee, Ikchoon,Kim, Hyung Yoon,Kang, Han Keun,Lee, Hai Whang

, p. 2678 - 2683 (2007/10/02)

Nucleophilic substitution reactions of 1-phenylethyl benzenesulfonates with anilines have been investigated in methanol-acetonitrile mixtures at 25 deg C.Magnitudes of the Hammett coefficients ρX, ρY, and ρZ indicate that

Arylalkyl amines useful for lowering intraocular pressure

-

, (2008/06/13)

Intraocular hypertensive diseases such as glaucoma are treated with compounds represented by formula I STR1 or a pharmaceutically acceptable acid addition salt thereof, wherein R1 is alkyl of two to four carbon atoms; R2 is --(CH2)n --C6 H4 --R5 ; where n is an integer from 1 to 4; and R5 is --H, --OH, halo, lower alkyl, lower alkoxy, ureido, lower alkyl-ureido, lower alkyl-amido, or formamido; R3 is hydro or hydroxy; and R4 is hydro, lower alkyl, amino, or lower alkylamino.

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