53510-49-9Relevant academic research and scientific papers
Silicon incorporation in polymethine dyes
Pengshung, Monica,Neal, Patrick,Atallah, Timothy L.,Kwon, Junho,Caram, Justin R.,Lopez, Steven A.,Sletten, Ellen M.
supporting information, p. 6110 - 6113 (2020/06/10)
Methods to red-shift fluorophores have garnered considerable interest due to the broad utility of low energy light. The incorporation of silicon into xanthene and coumarin scaffolds has resulted in an array of visible and near-infrared fluorophores. Here,
Improved Xanthone Synthesis, Stepwise Chemical Redox Cycling
Bachman, James L.,Escamilla, P. Rogelio,Boley, Alexander J.,Pavlich, Cyprian I.,Anslyn, Eric V.
supporting information, p. 206 - 209 (2019/01/10)
A base-catalyzed direct oxidation of rhodamine, carborhodamine, and siliconrhodamine pyronines to the corresponding xanthones is studied. This methodology utilizes addition of water to split pyronines into xanthone and reduced xanthene, the latter of whic
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum
Shieh, Peyton,Dien, Vivian T.,Beahm, Brendan J.,Castellano, Joseph M.,Wyss-Coray, Tony,Bertozzi, Carolyn R.
supporting information, p. 7145 - 7151 (2015/06/25)
Fluorescent bioorthogonal smart probes across the visible spectrum will enable sensitive visualization of metabolically labeled molecules in biological systems. Here we present a unified design, based on the principle of photoinduced electron transfer, to access a panel of highly fluorogenic azide probes that are activated by conversion to the corresponding triazoles via click chemistry. Termed the CalFluors, these probes possess emission maxima that range from green to far red wavelengths, and enable sensitive biomolecule detection under no-wash conditions. We used the CalFluor probes to image various alkyne-labeled biomolecules (glycans, DNA, RNA, and proteins) in cells, developing zebrafish, and mouse brain tissue slices.
