53525-65-8

Usage

Uses

Used in Pharmaceutical Industry:
5H,10H-Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione is used as a building block for the synthesis of pharmaceutical compounds due to its unique reactivity and versatility. It aids in the preparation of complex organic molecules with potential therapeutic applications.
Used in Materials Science:
In the field of materials science, 5H,10H-Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione is utilized as a component in the development of novel materials with specific properties. Its unique chemical structure and reactivity contribute to the creation of advanced materials with potential applications in various industries.
Used in Organic Synthesis:
5H,10H-Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione serves as a key intermediate in organic synthesis, enabling the preparation of a wide range of complex organic molecules. Its unique reactivity allows for the synthesis of compounds with diverse structures and functionalities, expanding the scope of organic chemistry.

Upstream product

• 1072-84-0 imidazole-4-carboxylic acid 
• 61985-23-7 methyl 1-imidazolecarboxylate 
• 17325-26-7 1H-imidazole-5-carboxylic acid methyl ester 
• 13189-13-4 5-(anilinocarbonyl)imidazole 
• 56460-32-3 imidazole-4-carboxylic acid chloride 
• 1072-84-0 3H-imidazole-4-carboxylic acid 

Downstream Products

• 23785-21-9 ethyl 1H-imidazole-4-carboxylate 
• 99240-58-1 4(5)-imidazole 
• 53525-55-6 1⁽³⁾H-imidazole-4-carboxylic acid methylamide 
• 69147-97-3 N-(2-Bromophenyl)-imidazole-4⁽⁵⁾-carboxamide 
• 111074-70-5 4⁽⁵⁾-(2,4-dichlorobenzylaminocarbonyl)imidazole 
• 240815-48-9 N-(2-chloro-3-pyridinyl)-1H-imidazole-4-carboxamide 
• 240815-51-4 3H-imidazole-4-carboxylic acid (2,6-dichloro-pyridin-3-yl)-amide 
• 357647-43-9 3H-imidazole-4-carboxylic acid (4-bromo-2-fluoro-phenyl)-amide 
• 357647-44-0 3H-imidazole-4-carboxylic acid (5-bromo-2,4-difluoro-phenyl)-amide 
• 53525-55-6 1⁽³⁾H-imidazole-4-carboxylic acid methylamide 
• 869491-11-2 N-cyclopropyl-1H-imidazole-4-carboxamide 
• 240815-48-9 N-(2-Chloro-3-pyridinyl)-1H-imidazole-4-carboxamide 
• 240815-51-4 N-(2,6-Dichloro-3-pyridinyl)-1H-imidazole-4-carboxamide 
• 1123512-68-4 N-(5-(5-(4-(difluoromethoxy)phenyl)pyrimidin-2-ylamino)-2-methylphenyl)-1H-imidazole-5-carboxamide 

Relevant academic research and scientific papers

Imidazo[1,2-a]pyrazine, Imidazo[1,5-a]quinoxaline and?Pyrazolo[1,5-a]quinoxaline derivatives as IKK1 and IKK2 inhibitors

The transcription nuclear factor NF-κB plays a pivotal role in chronic and acute inflammatory diseases. Among the several and diverse strategies for inhibiting NF-κB, one of the most effective approach considered by the pharmaceutical industry seems to be

In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives

Imidazoquinoxaline and pyrazoloquinoxaline derivatives, analogues of imiquimod, were synthesized, and their in vitro cytotoxic and pharmacodynamic activities were evaluated. In vitro cytotoxicity studies were assessed against melanoma (A375, M4Be, RPMI-75

DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR

A difluoroalkene derivative which is sufficiently effective in controlling various pests even when used in a small dose and is highly safe for crops, natural enemies to the pests, and animals; and an intermediate for the derivative. The difluoroalkene derivative is represented by the general formula: [I] wherein L1 and L2 are the same or different and each represents oxygen or sulfur; n is an integer of 2 to 8; and Q represents a 5- to 12-membered heterocyclic group having any desired heteroatom selected among nitrogen, oxygen, and sulfur.

Substituted pyrazolopyridopyridazines as orally bioavailable potent and selective PDE5 inhibitors: Potential agents for treatment of erectile dysfunction

Novel pyrazolopyridopyridazine derivatives have been prepared as potent and selective PDE5 inhibitors. Compound 6 has been identified as a more potent and selective PDE5 inhibitor than sildenafil (1). It is as efficacious as sildenafil in in vitro and in

Synthesis of imidazo[1,5-a]quinoxalin-4(5H)-one template via a novel intramolecular cyclization process

A novel, efficient, and regiospecific method for the construction of the imidazo[1,5-a]quinoxalin-4(5H)-one template is described. The key reaction involves an intramolecular cyclization process and provides the desired products in excellent yield.

Diazafulvenones. Thermal Isomerizations and Eliminations in Alkoxycarbonyl and Anilinocarbonyl Derivatives of Imidazole

4-Carbonyl-4H-imidazole (10) and 2-carbonyl-2H-imidazole (11) are formed by flash vacuum pyrolysis of methyl 4- and 2-imidazolecarboxylates, respectively. 10 and 11 dimerize to diketopiperazines 14 and 16, respectively.The same products are also obtained from 4- and 2-(anilinocarbonyl)imidazoles, respectively.Methyl imidazole-1-carboxylate (4) on pyrolysis gives a ca. 1:1 mixture of the same ketenes 10 and 11, which dimerizes to a 1:2:1 ratio of diketopiperazines 14-16.In contrast, ethyl imidazole-1-carboxylate gave CO2, ethylene, and imidazole as the major products.The pyrolysis reactions were monitored by low-temperature infrared and high-temperature mass spectrometry.