53531-20-7Relevant academic research and scientific papers
High linear selectivity ligand for allyl alcohol hydroformylation
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Page/Page column 7; 8, (2020/11/28)
A process for selectively producing 4-hydroxybutyraldehyde from allyl alcohol is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst system comprising a rhodium complex and a trans-1,2-bis(bis(3,4,5-tri-n-alkylphenyl)phosphinomethyl)-cyclobutane. The process gives high yield of 4-hydroxybutyraldehyde compared to temperature.
HYDROFORMYLATION PROCESS
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Page/Page column 9, (2010/12/17)
A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a trans-1,2-bis(bis(3,4-di-n-alkylphenyl)phosphinomethyl)cyclobutane and/or a 2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis[bis(3,4-di-n-alkylphenyl)phosphino] butane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.
Preparation of diphenyl phosphide and substituted phosphines using alkali metal in silica gel (M-SG)
Nandi, Partha,Dye, James L.,Bentley, Philip,Jackson, James E.
supporting information; experimental part, p. 1688 - 1692 (2009/09/06)
Alkali metals absorbed in silica gel (the M-SG reagents) efficiently cleave C-P bonds in triaryl- and diarylphosphines. The resulting alkali metal phosphides can serve as useful building blocks for a variety of phosphines. Alkyldiarylphosphines undergo exclusive aryl group cleavage.
Modification of ligand properties of phosphine ligands for C-C and C-N bond-forming reactions
Morris, David J.,Docherty, Gordon,Woodward, Gary,Wills, Martin
, p. 949 - 953 (2008/02/04)
A series of ligands have been prepared for use in Pd-catalysed coupling reactions to form C-C and C-N bonds; significant differences are exhibited by similar ligands containing different phosphorus substituents.
Decarboxylative aldol reactions of allyl β-keto Esters via heterobimetallic catalysis
Lou, Sha,Westbrook, John A.,Schaus, Scott E.
, p. 11440 - 11441 (2007/10/03)
Mild and selective heterobimetallic-catalyzed decarboxylative aldol reactions involving allyl β-keto esters have been developed. The reaction is promoted by Pd(0)- and Yb(III)-DIOP complexes at room temperature and involves the in situ formation of a ketone enolate from allyl β-keto esters followed by addition of the enolate to aldehydes. The reaction is a new example of heterobimetallic catalysis in which the optimized reaction conditions require the addition of both metals. Copyright
Process for preparing optically active 1-(p-methoxybenzyl)-1,2,3,4,5,3,7,8-octahydroisoquinoline
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, (2008/06/13)
Optically active 1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline having the formula (I) is prepared by asymmetric hydrogenation of the corresponding 3,4,5,6,7,8-hexahydro-compound or of the new 1-(p-methoxybenzyl)-3,4,5,6,7,8-hexahydroisoquinoline dihydrogenated phosphate in the present of chiral iridium-phosphine complexes. This product is an intermediate product in the synthesis of cough-relieving dextromethorphanne and analgesic levorphanol. STR1
Production of primary and secondary amines by reaction of ammonia with conjugated diene in the presence of Pd/phosphine catalyst and primary or secondary aliphatic alcohol solvent medium
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, (2008/06/13)
Short chain, unsaturated primary and secondary amines are prepared by reaction of ammonia and conjugated dienes in a primary or secondary aliphatic alcohol solvent medium and in the presence of a catalyst system comprising a palladium compound co-catalyzed with a phosphine ligand containing 2 to 4 phosphorus atoms.
