53589-56-3

Upstream product

• 75-21-8 oxirane 
• 115-18-4 2-methyl-3-buten-2-ol 
• 35189-96-9 3-methyl-2-butenylmagnesium chloride 
• 540-51-2 2-bromoethanol 

Downstream Products

• 947758-46-5 6,6-difluoro-4-iodo-3,3-dimethyl-6-(3-phenyl-1,2,4-oxadiazol-5-yl)hexan-1-ol 
• 691871-15-5 (4R,5S)-4-Allyl-3-(3,3-dimethyl-pent-4-enyl)-5-isopropenyl-2,4-dimethyl-cyclohex-2-enone 
• 691871-09-7 (4S,5S)-4-Allyl-3-(3,3-dimethyl-pent-4-enyl)-5-isopropenyl-2,4-dimethyl-cyclohex-2-enone 
• 691871-11-1 (4S,5R)-4-Allyl-3-(3,3-dimethyl-pent-4-enyl)-2,4-dimethyl-5-((S)-2-methyl-oxiranyl)-cyclohex-2-enone 
• 691871-17-7 (4R,5R)-4-Allyl-3-(3,3-dimethyl-pent-4-enyl)-2,4-dimethyl-5-((S)-2-methyl-oxiranyl)-cyclohex-2-enone 

Relevant academic research and scientific papers

Tailor-made silylating agents for efficient surface modification

N-Silyldimethylamines are efficient silylating agents for the chemical surface modification of hydroxylated silicon dioxide preparations. The synthesis of chloro(5-X-3,3-dimethylpentyl)-dimethyl-silanes and their conversion to the corresponding (dimethylamino) silanes are described, where X is a methoxy, methoxymethoxy, cyano or dimethylamino group. The bulky substituent forms a two stage protecting layer at the surface. The second stage hinders the access of nucleophiles to the silicon atom resulting an enhanced hydrolytic stability.

Condensation de reactifs organomagnesiens sur les bromhydrines du type R-CH(Br)-CH2OH. Influence des sels cuivreux.

Various allylic, vinylic and arylic Grignard reagents are able to condense with 2-bromo-1-alkanols in THF.The catalytic use of copper salts diminishes side reactions but is not required.