53596-71-7

Basic information

• Product Name: 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE
• Synonyms: 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE;2',4'-Dihydroxydihydrochalcone
• CAS NO: 53596-71-7
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.27
• Product Categories: Chalcones
• Mol File: 53596-71-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE(53596-71-7)
• EPA Substance Registry System: 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE(53596-71-7)

Safety Data

• Hazardous Substances Data: 53596-71-7(Hazardous Substances Data)

Usage

General Description

2',4'-dihydroxy-4-methoxydihydrochalcone is a chemical compound found in plants such as Angelica keiskei, also known as ashitaba. It is classified as a chalcone, a type of flavonoid compound. 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE has shown antioxidant, anti-inflammatory, and anti-cancer properties in various studies. It has potential therapeutic effects on various health conditions such as obesity, diabetes, and cardiovascular diseases. Additionally, it has been studied for its potential use in skincare and cosmetic products due to its antioxidant and anti-aging properties. Overall, 2',4'-dihydroxy-4-methoxydihydrochalcone shows promising potential for various health and cosmetic applications.

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Relevant articles and documents

Synthesis and biological activity of (±)-7,3′,4′-trihydroxyhomoisoflavan and its analogs

Acetylcholinesterase (AChE) inhibitors and neurite outgrowth promoters are thought to alleviate the symptoms of degenerative brain disorders, such as Alzheimer's disease. We designed and synthesized a series of homoisoflavonoids based on the structure of natural homoisoflavan isolated from Dracaena cambodiana dragon's blood. The homoisoflavonoids were then evaluated as AChE inhibitors and neurite outgrowth promoters. The catechol structure of the homoisoflavan B rings was important for AChE inhibition, and some of the homoisoflavonoids significantly promoted neurite outgrowth induced by nerve growth factor (NGF).

Development of 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs) from natural isoflavones, a new class of fluorescent scaffolds for biological imaging

Starting from 7-hydroxyisoflavones, we developed a new class of fluorescent scaffolds, 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs, MW ～ 205.19, λab ～ 350 nm, λem ～ 450 nm) via a trial and error process. AMHCs have the advantages of being a small molecular moiety, having strong fluorescence in basic buffers, reasonable solubility and stability, non-toxicity, and are conveniently linked to pharmacophores. AMHCs were successfully used in fluorescence microscopy imaging of cells and tissues. This journal is