53597-71-0Relevant academic research and scientific papers
Solvent-free N-alkylation of 1,3,5-triaza-7: phospha-adamantane (PTA)
Udvardy, Antal,Szolnoki, Csenge Tamara,Joó, Ferenc,Kathó, ágnes
, p. 469 - 470 (2019)
1,3,5-triaza-7-phosphaadamantane was alkylated under solvent-free conditions with CH3I, CH3-(CH2)3-Br, Br-(CH2)4-Br, OH-CH2-CH2Br, and CH3CH2OOCCH2Br in a planetary ball mill with yields over 90%. Due to spontaneous resolution, both 1-(2-ethoxy-2-oxoethyl)-3,5-diaza-1-azonia-3,5-diaza-7-phosphaadamantane bromide (4) and (4-bromobutyl)-1-azonia-3,5-diaza-7-phosphaadamantane bromide (5) were obtained in the solid state as conglomerates of enantiomorphic crystals.
A 31P NMR STUDY OF THE WATER SOLUBLE DERIVATIVES OF 1,3,5-TRIAZA-7-PHOSPHAADAMANTANE (PTA)
Fisher, Keith J.,Alyea, Elmer C.,Shahnazarian, Noel
, p. 37 - 40 (2007/10/02)
1,3,5-Triaza-7-phosphaadamantane (PTA), a small air stable aliphatic phosphine, and some water soluble derivatives have been studied mainly using 31P nmr.PTA has been shown to have a pKa of 6.0 but this basicity does not relate to the phosphorus atom but one of the nitrogen atoms in the molecule.Alkyl halides similarly add to one of the nitrogens and conductivity and nmr studies indicate that these are ammonium salts.Oxidation and the reaction with sulphur and selenium occur at phosphorus, indicated by large 31P coordination chemical shifts.All the derivatives prepared are water soluble.
