535975-28-1Relevant academic research and scientific papers
1-Trifluoromethylvinylsilane as a CF2=C--CH 2+ synthon: Synthesis of functionalized 1,1-difluoro-1-alkenes via isolable 2,2-difluorovinylsilanes
Ichikawa, Junji,Fukui, Hiroki,Ishibashi, Yuichiro
, p. 7800 - 7805 (2007/10/03)
Various 1,1-difluoro-1-alkenes such as monosubstituted 1,1-difluoro-1-alkenes, 2-bromo-1,1-difluoro-1-alkenes, and 3,3-difluoroallylic alcohols are synthesized in two simple steps from 1-trifluoro-methylvinylsilane: (i) its SN2′ reaction with n
A novel synthesis of functionalized 1,1-difluoro-1-alkenes via isolable 2,2-difluorovinylsilanes
Ichikawa, Junji,Ishibashi, Yuichiro,Fukui, Hiroki
, p. 707 - 710 (2007/10/03)
Various 1,1-difluoro-1-alkenes such as monosubstituted 1,1-difluoro-1-alkenes, 2-bromo-1,1-difluoro-1-alkenes, and 1,1-difluoro-3-hydroxy-1-alkenes are prepared in two simple steps from 1-trifluoromethylvinylsilane: (i) its SN2′ reaction with nucleophiles to construct 2,2-difluorovinylsilanes and (ii) the subsequent substitution of electrophiles for the vinylic silyl group.
