535975-23-6

Upstream product

• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 768-33-2 phenyldimethylsilyl chloride 
• 754-12-1 2,3,3,3-tetrafluoro-propene 
• 185990-03-8 dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane 

Downstream Products

• 535975-35-0 [2-(dimethylphenylsilyl)-3,3-difluoroallyl]diisopropylamine 
• 535975-30-5 [2,2-difluoro-1-(2-phenyl-1,3-dithian-2-ylmethyl)vinyl]dimethylphenylsilane 
• 535975-28-1 (2,2-difluoro-1-undecylvinyl)dimethylphenylsilane 
• 612816-84-9 2-benzyl-4-(dimethylphenylsilyl)-5,5-difluoro-N,N-dimethyl-4-pentenamide 
• 1433609-23-4 N’-[3,3-difluoro-2-(dimethylphenylsilyl)prop-2-en-1-yl]-N’-phenyl-p-toluenesulfonohydrazide 
• 1433609-17-6 N’-[3,3-difluoro-2-(dimethylphenylsilyl)prop-2-en-1-yl]-N’-tert-butoxycarbonyl-p-toluenesulfonohydrazide 
• 899437-07-1 N-{o-[3,3-difluoro-2-(dimethylphenylsilyl)prop-2-en-1-yl]phenyl}-p-toluenesulfonamide 
• 899437-08-2 3-fluoro-3-(dimethylphenylsilyl)-1-(p-toluenesulfonyl)-1,4-dihydroquinoline 
• 899437-05-9 3,3-difluoro-[o-(2-dimethylphenylsilyl)prop-2-en-1-yl]aniline 

Relevant academic research and scientific papers

A novel synthesis of functionalized 1,1-difluoro-1-alkenes via isolable 2,2-difluorovinylsilanes

Various 1,1-difluoro-1-alkenes such as monosubstituted 1,1-difluoro-1-alkenes, 2-bromo-1,1-difluoro-1-alkenes, and 1,1-difluoro-3-hydroxy-1-alkenes are prepared in two simple steps from 1-trifluoromethylvinylsilane: (i) its SN2′ reaction with nucleophiles to construct 2,2-difluorovinylsilanes and (ii) the subsequent substitution of electrophiles for the vinylic silyl group.

Fluorinated Vinylsilanes from the Copper-Catalyzed Defluorosilylation of Fluoroalkene Feedstocks

Herein, a copper-catalyzed C?F bond defluorosilylation reaction of tetrafluoroethylene and other polyfluoroalkenes is described. Mechanistic studies, based on a series of stoichiometric reactions with copper complexes, revealed that the key steps of this defluorosilylation reaction are 1) the 1,2-addition of a silylcopper intermediate to the polyfluoroalkene and 2) a subsequent selective β-fluorine elimination, which generates a Cu?F species. The β-fluorine elimination is facilitated by Lewis acidic F?Bpin, which is generated in situ during the defluorosilylation.

METHOD FOR PRODUCING SUBSTITUTED OLEFIN COMPOUND

PROBLEM TO BE SOLVED: To provide a new method for producing a substituted olefin compound, in particular, a new method for producing a fluorine-containing olefin substituted with a boron-containing group or a silicon-containing group. SOLUTION: There is provided a method for producing a compound represented by the formula (1), which comprises a step of reacting a fluorinated olefin with a compound represented by the formula (3).[R1 to R3 represent H, F, an organic group or the like; RX represents -BX2 or -SiX3; X represents H, a halogen or an organic group; provided that X may form a ring together with adjacent B or Si; Y1 and Y2 each independently represent OH or an alkoxy group; provided that Y1 and Y2 may form a ring together with adjacent B.] SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT

1-Trifluoromethylvinylsilane as a CF2=C--CH 2+ synthon: Synthesis of functionalized 1,1-difluoro-1-alkenes via isolable 2,2-difluorovinylsilanes

Various 1,1-difluoro-1-alkenes such as monosubstituted 1,1-difluoro-1-alkenes, 2-bromo-1,1-difluoro-1-alkenes, and 3,3-difluoroallylic alcohols are synthesized in two simple steps from 1-trifluoro-methylvinylsilane: (i) its SN2′ reaction with n