53611-44-2

Usage

Uses

Used in Chemical Synthesis:
6-Ethyl-2-piperidinone is used as a chemical intermediate for its reactivity in various chemical reactions. Its structure allows it to be a key component in the synthesis of more complex molecules, contributing to the development of new compounds and materials.
Used in Pharmaceutical Industry:
6-Ethyl-2-piperidinone is used as a building block in the pharmaceutical industry for the development of new drugs. Its unique structure and reactivity make it a valuable component in the synthesis of potential therapeutic agents.
Used in Research and Development:
6-Ethyl-2-piperidinone is used as a research compound in academic and industrial laboratories. It serves as a model compound for studying the properties and reactions of piperidinones, which can lead to a better understanding of their potential applications and limitations.

InChI:InChI=1/C7H13NO/c1-2-6-4-3-5-7(9)8-6/h6H,2-5H2,1H3,(H,8,9)

Upstream product

• 64847-88-7 2-ethylcyclopentanone 
• 98-09-9 benzenesulfonyl chloride 
• 1121-89-7 piperidine-2,6-dione 
• 925-90-6 ethylmagnesium bromide 
• 1484-80-6 2-ethylpiperidine 
• 7664-93-9 sulfuric acid 
• 98435-37-1 2-Ethylcyclopentanone oxime 

Relevant academic research and scientific papers

Direct Catalytic Desaturation of Lactams Enabled by Soft Enolization

A direct catalytic method is described for the α,β-desaturation of N-protected lactams to their conjugated unsaturated counterparts under mildly acidic conditions. The reaction is consistently operated at room temperature and tolerates a wide range of functional groups, showing reactivity complementary to that of prior desaturation methods. Lactams with various ring sizes and substituents at different positions all reacted smoothly. The synthetic utility of this method is demonstrated in a concise synthesis of Rolipram. In addition, linear amides also prove to be competent substrates, and the phthaloyl-protected product serves as a convenient precursor to access various conjugated carboxylic acid derivatives. Strong bases are avoided in this desaturation approach, and the key is to merge soft enolization with a Pd-catalyzed oxidation process.

THIOPHENE DERIVATIVE

The present invention provides a compound represented by the formula (I) or its salt, solvate, or physiologically functional derivative; and a pharmaceutical composition which is useful for treatment or prevention of conditions or disorders having sensitivity to selective androgen receptor modulation, the composition comprising the above-described compound; among others:

Pushing radical cyclization from regioselective to regiospecific: Cyclization of amidyl radicals controlled by vinylic halogen substitution

Efficient and regiospecific 6-exo, 7-endo, 7-exo, and even 8-endo amidyl radical cyclizations can be accomplished by the direct reactions of unsaturated N-H amides if they bear a vinylic halogen (Cl, Br, I) substituent. This remarkable halogen-substitution effect could be rationalized in terms of lone pair-lone pair electron repulsion between the N radical and the vinylic halogen atom, in addition to the well-known steric and radical-stabilizing effect.

NOVEL QUINOXALINE DERIVATIVES

A quinoxalinone derivative of the formula (I): or a pharmaceutically acceptable salt or ester thereof, wherein; ???X is NH, S or the like; ???Y is O or the like; ???the partial structure is, for example, the formula: ???B1, B2, ....., Bn-1 and Bn, (in which n is 4 , 5 or 6) are each independently CH, N or the like; ???B'1, B'2, ....., B'n-1 and B'n (in which n is 4, 5 or 6) are each independently hydrogen or the like; and ???R is hydrogen, lower alkyl or the like.

Liquid phase oxidation of saturated nitrogen-containing heterocyclics over modified MCM-41 molecular sieves

For the first time, the liquid phase oxidation reactions of saturated N-heterocyclics like piperidine and pyrrolidine to piperidone and pyrrolidone have been carried out over modified MCM-41 molecular sieves with 30-55% yield and >80% selectivity.

Amidino derivatives useful as nitric oxide synthase inhibitors

The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.

Amidino dervatives useful as nitric oxide synthase inhibitors

The current invention discloses useful pharmaceutical compositions containing azepine derivatives useful as nitric oxide synthase inhibitors.