53616-34-5Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
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Paragraph 0435-0436, (2019/01/15)
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
A formal synthesis of aflatoxin B2: a Doetz benzannulation approach
Eastham, Stephan A.,Ingham, Steven P.,Hallett, Michael R.,Herbert, John,Quayle, Peter,Raftery, James
, p. 2299 - 2304 (2007/10/03)
A Doetz benzannulation reaction has been utilized in the synthesis of the furo[2,3-b]furan core of aflatoxin B2.
A new route to 2,7- and 7-functionalized labdanes
Hersel, Ulrich,Steck, Melanie,Seifert, Karlheinz
, p. 1609 - 1615 (2007/10/03)
A new route for the synthesis of 2,7- and 7-functionalized labdanes starts from (R)-carvone (1). 11-Nordrim-7-en-9-one (15) is an appropriate starting material for the total synthesis of hispanone (21), a biologically active furolabdane isolated from the
The first enantioselective synthesis of (-)-microcionin 2
Potvin, Steeves,Canonne, Persephone
, p. 2821 - 2824 (2007/10/03)
An approach known to give regiospecific and stereospecific reactions has been applied to the enantioselective synthesis of the natural (-)-microcionin 2 (1), a prototype of trans relationship of the methyl groups on the furanosesquiterpenes.
CHIRAL PRECURSORS FOR SYNTHESES OF FURANOTERPENES
Marco, Jose L.
, p. 1475 - 1490 (2007/10/02)
The synthesis of (2S,4R,5R) and (2R,4R,5R)-2-(3-furyl)-4,5-isopropylidenedioxytetrahydrofuran (4 and 5) and (2S,4R,5S)-5-ethoxy-2-(3-furyl)-4-hydroxytetrahydrofuran (37) from "diacetone glucose" (6) is described.A new approach to 1-(R) and 1-(S)-(3-furyl)
SYNTHESIS OF OPTICALLY PURE 1-(3-FURYL)-1,2-DIHYDROXYETHANE DERIVATIVES
Marco, Jose L.,Hueso-Rodriguez, Juan A.
, p. 2459 - 2462 (2007/10/02)
The synthesis of the enantiomerically pure 1-(3-furyl)-1,2-dihydroxyethane derivatives 1-(R), 2-(R), 3-(S) and 3-(R) is described.
