53617-93-9Relevant academic research and scientific papers
ELECTROCHEMICAL CROSS-COUPLING OF ORGANIC HALIDES: TRICHLORMETHYLATION AND RELATED SYNTHESIS OF GEM-DICHLORO COMPOUNDS
Nedelec, J. Y.,Ait-Haddou-Mouloud, H.,Folest, J. C.,Perichon, J.
, p. 1699 - 1700 (2007/10/02)
The cross-coupling of activated alkyl halides with carbon tetrachloride or substituted trichloromethanes can be obtained electrochemically in good yield in an undivided cell with a sacrificial anode.
Electrochemical Cross-Coupling of Alkyl Halides in the Presence of a Sacrificial Anode
Nedelec, Jean-Yves,Mouloud, Hassan Ait Haddou,Folest, Jean-Claude,Perichon, Jacques
, p. 4720 - 4724 (2007/10/02)
The electrochemical trichloromethylation of various alkyl halides has been obtained in high yields in an undivided cell in the presence of a sacrificial anode.This cross-coupling process has been extended to the preparation of numerous gem-dichloro compounds from trichloro-substituted methanes and alkyl halides.Zinc,magnesium or aluminium were used as anodes according to the reduction potentiel of the reagents.Mixtures of polar aprotic solvents,e.g.THF-TMU or THF-NMP, were found more appropriate than pure solvents.The critical role of the metallic ions from the consumption of the anode has been clearly evidenced.
