53621-95-7Relevant academic research and scientific papers
The chemistry of phosphapeptides: Formation of functionalized phosphonochloridates under mild conditions and their reaction with alcohols and amines
Malachowski,Coward
, p. 7616 - 7624 (1994)
A variety of methods have been explored for the convergent synthesis of phosphonamidates and phosphonates via phosphonochloridates. In the absence of complex functionality, phosphorus pentachloride is an effective reagent for the conversion of diethyl and
Synthesis of alkyl hydrogen alkylphosphonates
Pienaar, Andre,Erasmus, Cornelis M.,Wentzel, Mauritz,Cowley, Eugene H.
, p. 149 - 159 (2007/10/03)
The synthesis of alkyl hydrogen alkylphosphonates 1 was studied. Different synthetic routes were investigated and it was found that alkylphosphonic anhydrides can serve as ideal precursors for the synthesis of those half-acids. It was also shown that isopropyl phosphonic dichloride reacts in a unique fashion to produce alkyl hydrogen isopropylphosphonates in moderate yields.
