53646-87-0Relevant academic research and scientific papers
A New Two-Step Preparation of Pyrroles from β-Amino Ketones Utilizing Trimethylsilyldiazomethane
Yagi, Tsutomu,Aoyama, Toyohiko,Shioiri, Takayuki
, p. 1063 - 1064 (1997)
Lithium trimethylsilyldiazomethane smoothly reacted with N-substituted β-amino ketones to give 2-pyrrolines which were easily converted to the corresponding pyrroles by treatment with MnO2 (CMD, chemical manganese dioxide). The reaction with N,N-disubstituted β-amino ketones followed by oxidation with CMD also afforded pyrroles.
