53658-03-0

Basic information

• Product Name: Benzonitrile, 4,4'-[1,4-phenylenebis(methyleneoxy)]bis-
• CAS NO: 53658-03-0
• Molecular Formula: C22H16N2O2
• Molecular Weight: 340.381
• Mol File: 53658-03-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4,4'-[1,4-phenylenebis(methyleneoxy)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4,4'-[1,4-phenylenebis(methyleneoxy)]bis-(53658-03-0)
• EPA Substance Registry System: Benzonitrile, 4,4'-[1,4-phenylenebis(methyleneoxy)]bis-(53658-03-0)

Safety Data

• Hazardous Substances Data: 53658-03-0(Hazardous Substances Data)

Upstream product

• 623-24-5 1,4-bis(bromomethyl)benzene 
• 767-00-0 4-cyanophenol 
• 3328-57-2 sodium 4-cyanophenolate 

Downstream Products

• 118499-86-8 1,4-Bis(4-amidoximinophenoxymethyl)benzene 
• 53657-95-7 1,4-bis{(4-amidino)-phenoxymethyl}benzene dihydrochloride 
• 75846-17-2 4,4′-((1,4-phenylenebis(methylene))bis(oxy))dibenzimidamide 

Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS

Compounds and methods for use to treat a bacterial infection caused by, for example, gram positive bacteria, gram negative bacteria, and/or mycobacteria are provided herein. Also provided herein are compounds and methods for use in potentiating the effect of an antibiotic in the treatment of a bacterial infection. Pharmaceutical compositions including the compounds as described herein are also provided.

AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS

Compounds and methods for the treatment of a bacterial infection or the potentiation of an antibiotic in treating a bacterial infection are described herein.

Novel bisbenzamidines as potential drug candidates for the treatment of Pneumocystis carinii pneumonia

A series of pentamidine congeners has been synthesized and screened for their in vitro activity against Pneumocystis carinii. Among the tested compounds, bisbenzamidines linked by a flexible pentanediamide or hexanediamide chain (7 and 9) emerged as excep