536739-11-4

Basic information

• Product Name: [(R)-Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-phosphonic acid diallyl ester
• Synonyms: [(R)-Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-phosphonic acid diallyl ester
• CAS NO: 536739-11-4
• Molecular Weight: 336.248
• Mol File: 536739-11-4.mol

Chemical Properties

• CAS DataBase Reference: [(R)-Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-phosphonic acid diallyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(R)-Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-phosphonic acid diallyl ester(536739-11-4)
• EPA Substance Registry System: [(R)-Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-phosphonic acid diallyl ester(536739-11-4)

Safety Data

• Hazardous Substances Data: 536739-11-4(Hazardous Substances Data)

Upstream product

• 146780-08-7 O,O-Diethyl 3-Trifluoromethylphenylmethylphosphonate 
• 536739-01-2 (3-trifluoromethyl-benzyl)-phosphonic acid diallyl ester 

Relevant articles and documents

Chiral, non-racemic α-hydroxyphosphonates and phosphonic acids via stereoselective hydroxylation of diallyl benzylphosphonates

Chiral, non-racemic α-hydroxyphosphonates have been prepared in high enantiomeric excess (96-98% ee), via stereoselective oxaziridine-mediated hydroxylation of diallyl benzylphosphonates. The enantiomeric purity and absolute configuration of the α-hydroxy

Stereoselective synthesis of phosphoramidate α(2-6)sialyltransferase transition-state analogue inhibitors

The asymmetric synthesis of novel, potent phosphoramidate α(2-6)sialyltransferase transition-state analogue inhibitors such as (R) -9 (Ki=68 μM) is described, via condensation of cytidine phosphitamide 6 with key chiral, non-racemic α-aminophosphonates, prepared in >98% ee by Mitsunobu azidation followed by Staudinger reduction of the corresponding chiral, non-racemic α-hydroxyphosphonates.