5369-30-2Relevant academic research and scientific papers
Highly selective sp3 C-N bond activation of tertiary anilines modulated by steric and thermodynamic factors
Jia, Xiaodong,Li, Pengfei,Shao, Yu,Yuan, Yu,Ji, Honghe,Hou, Wentao,Liu, Xiaofei,Zhang, Xuewen
supporting information, p. 5568 - 5574 (2017/12/06)
A highly selective sp3 C-N cleavage of tertiary anilines was achieved using the TBN/TEMPO catalyst system. When N,N-diaklylanilines (alkyl, benzyl) were employed, the N-CH3 bond was selectively cleaved via radical C-H activation. Moreover, when the allyl group was installed, totally reverse selectivity was observed. It is worth noting that the solvent effect is also crucial to obtain high reaction efficiency and selectivity.
Evidence for radical cations in linked mechanisms of N,N-Dialkyl aromatic amine nitration and nitrosative dealkylation
Loeppky, Richard N.,Singh, Sukhjeet P.,Elomari, Saleh,Hastings, Riley,Theiss, Thomas E.
, p. 5193 - 5202 (2007/10/03)
N,N,-Dialkyl aromatic amines react rapidly with nitrous acid to competitively produced a nitrosamine and a nitro compound. The mechanism of nitro compound formation involves a reaction of an amine radical cation with NO2, while the nitrosamine
SYNTHESIS OF DIHYDRO-2-(2-PHENYL-INDOLE-3-YL)-4-ARYL-1,5-BENZOTHIAZEPINES
Dandia, Anshu,Sehgal, Varinder,Upreti, Mani
, p. 93 - 99 (2007/10/03)
A series of novel dihydro-2-(2-phenyl-indole-3-yl)-4-aryl-1,5-benzothiazepines(III) have been synthesized by the reaction of 2-aminothiophenol with 2-phenyl-3-(3-aryl-3-oxo-propen-1-yl)-indoles (I) in ethanol and gl.acetic acid mixture.Chalcones (I) were
Nitrones and Oxaziridines. XLII Synthesis of Indol-3-yl Substituted 1-Pyrroline 1-Oxides
Black, David St.C.,Deb-Das, Renu B.,Kumar, Naresh
, p. 611 - 621 (2007/10/02)
The 1-pyrroline 1-oxides (13), (14), (16) and (18) with indol-3-yl substituents attached to the 2- or 4-positions have been synthesized by reductive cyclization of the related γ-nitro ketones.The corresponding 1-pyrrolines (15), (17) and (19) have also be
