53692-01-6

Upstream product

• 14204-24-1 N-(phenylthio)succinimide 
• 106-47-8 4-chloro-aniline 
• 33358-41-7 (5-chloro-2-nitro-phenyl)-phenyl sulfide 

Downstream Products

• 56447-25-7 5-chloro-2-(phenylthio)acetanilide 
• 37930-74-8 4-Chlor-2-phenylthio-trifluormethansulfonanilid 

Relevant academic research and scientific papers

Arylthiolation of arylamine derivatives with (arylthio)-pyrrolidine-2,5-diones

A simple and efficient method for arylthiolation of arylamines has been developed. The protocol uses (arylthio)pyrrolidine-2,5-diones as the arylthiolating reagents, acetonitrile as the solvent, and no catalyst and additive are required, which avoids contamination from the transition metal catalysts in the target products. Therefore, the present method should provide a convenient, efficient and practical strategy for the synthesis of other aryl sulfides.

CCR9 INHIBITORS AND METHODS OF USE THEREOF

The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.