53693-50-8Relevant academic research and scientific papers
A mild, one-pot synthesis of arylamines via palladium-catalyzed addition of aryl aldehydes with amines and arylboronic acids in water
Yu, Ajuan,Wu, Yangjie,Cheng, Baoli,Wei, Kun,Li, Jingya
supporting information; experimental part, p. 767 - 771 (2009/12/01)
A mild, one-pot synthesis of diarylmethylamines via the palladium-catalyzed addition of aryl aldehydes with amines and arylboronic acids is reported. Best results were obtained in neat water with ammonium chloride as additive, affording diarylmethylamine
Electronic and steric control in regioselective addition reactions of organolithium reagents with enaldimines
Tomioka,Shioya,Nagaoka,Yamada
, p. 7051 - 7054 (2007/10/03)
A reaction mode of imines derived from naphthalene-1-carbaldehyde and acyclic α,β-unsaturated aldehydes with organolitium reagents was dependent on the characteristic nature of a substituent on the imine nitrogen atom. An imine having an electron-withdrawing aryl group on the nirtogen atom behaves as a 1,2-directing imine toward organolithium reagents. In contrast, an imine bearing an alkyl or a bulky aryl group favors 1,4-addition of organolithium reagents. Electronic and steric tuning of a substituent on the imine nitrogen atom for a reaction mode was rationalized on the basis of molecular orbital calculations.
