536974-86-4

Basic information

• Product Name: 4-BENZYLOXY-3-CHLORO-BENZOIC ACID METHYL ESTER
• Synonyms: RARECHEM AL BF 0478;4-BENZYLOXY-3-CHLORO-BENZOIC ACID METHYL ESTER
• CAS NO: 536974-86-4
• Molecular Formula: C₁₅H₁₃ClO₃
• Molecular Weight: 276.71
• Mol File: 536974-86-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-BENZYLOXY-3-CHLORO-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-3-CHLORO-BENZOIC ACID METHYL ESTER(536974-86-4)
• EPA Substance Registry System: 4-BENZYLOXY-3-CHLORO-BENZOIC ACID METHYL ESTER(536974-86-4)

Safety Data

• Hazardous Substances Data: 536974-86-4(Hazardous Substances Data)

Upstream product

• 3964-57-6 methyl 4-hydroxy-3-chlorobenzoate 
• 100-39-0 benzyl bromide 
• 3964-58-7 3-chloro-4-hydroxybenzoic acid 
• 159465-83-5 benzyl 4-(benzyloxy)-3-chlorobenzoate 

Downstream Products

• 106931-79-7 4-(benzyloxy)-3-chlorobenzoic acid 
• 536974-87-5 (4-benzyloxy-3-chlorophenyl)methanol 
• 184841-34-7 C₂₇H₃₅ClN₂O₈ 
• 1027604-35-8 C₂₀H₂₉ClN₂O₈ 
• 184841-33-6 (2S,3R)-2-Acetylamino-3-(4-benzyloxy-3-chloro-phenyl)-3-hydroxy-propionic acid methyl ester 
• 184841-30-3 2-Acetylamino-3-(4-benzyloxy-3-chloro-phenyl)-3-oxo-propionic acid methyl ester 
• 184841-32-5 3-(4-Benzyloxy-3-chloro-phenyl)-2-[(E)-hydroxyimino]-3-oxo-propionic acid methyl ester 
• 271800-14-7 (2S,3R)-2-Acetylamino-3-(3-chloro-4-hydroxy-phenyl)-3-hydroxy-propionic acid methyl ester 
• 184841-31-4 (S)-3-(4-Benzyloxy-3-chloro-phenyl)-3-hydroxy-propionic acid methyl ester 
• 184841-29-0 3-(4-Benzyloxy-3-chloro-phenyl)-3-oxo-propionic acid methyl ester 
• 123436-73-7 4-benzyloxy-3-chlorobenzoic acid chloride 

Relevant articles and documents

SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES

The present invention relates to novel substituted 4-benzyloxy-benzoic acid amide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor overactivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).

Syntheses of the syn and anti α-amino-β-hydroxy acids of vancomycin: (2S, 3R) and (2R, 3R) p-chloro-3-hydroxytyrosines

Syntheses of (2S, 3R) and (2R, 3R) methyl p-chloro-3-hydroxytyrosinates 2 and 3 respectively, have been achieved from 3-chloro-4-hydroxybenzoic acid. These approaches relied on the asymmetric hydrogenation of highly functionalized carbonyl derivatives using chiral ruthenium complexes.