536975-31-2

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 6793-92-6 p-benzyloxyphenylbromide 
• 100-39-0 benzyl bromide 
• 611-99-4 4,4'-Dihydroxybenzophenone 
• 40076-84-4 4,4'-bis(benzyloxy)benzophenone 

Downstream Products

• 577994-61-7 3,3-bis[4-(benzyloxy)phenyl]propene 
• 536975-32-3 1-[Bis-(4-Benzyloxyphenyl)methyl]-1H-[1,2,4]triazole 
• 536975-09-4 bis(4-benzyloxyphenyl)chloromethane 
• 1454798-17-4 4,4'-(3-hydroxy-2-phenylpropane-1,1-diyl)diphenol 
• 1454798-16-3 4,4',4''-(3-hydroxypropane-1,1,2-triyl)triphenol 
• 1454798-15-2 4,4'-(3-hydroxy-2-p-tolylpropane-1,1-diyl)diphenol 
• 1454798-14-1 4,4'-(3-hydroxy-2-(3-methoxyphenyl)propane-1,1-diyl)diphenol 
• 1454798-13-0 4,4'-(3-hydroxy-2-(4-methoxyphenyl)propane-1,1-diyl)diphenol 
• 1454798-12-9 ethyl 2-(4-hydroxy-3-methoxyphenyl)-3,3-bis(4-hydroxyphenyl)propanoate 
• 1454798-11-8 ethyl 3,3-bis(4-hydroxyphenyl)-2-phenylpropanoate 
• 1454798-10-7 ethyl 2,3,3-tris(4-hydroxyphenyl)propionate 
• 1454798-09-4 ethyl 3,3-bis(4-hydroxyphenyl)-2-p-tolylpropanoate 
• 1454798-08-3 ethyl 3,3-bis(4-hydroxyphenyl)-2-(3-methoxyphenyl)propanoate 
• 1454798-07-2 ethyl 3,3-bis(4-hydroxyphenyl)-2-(4-methoxyphenyl)propanoate 

Relevant academic research and scientific papers

Synthesis and antiproliferative activities of quebecol and its analogs

Simple and efficient synthesis of quebecol and a number of its analogs was accomplished in five steps. The synthesized compounds were evaluated for antiproliferative activities against human cervix adenocarcinoma (HeLa), human ovarian carcinoma (SK-OV-3), human colon carcinoma (HT-29), and human breast adenocarcinoma (MCF-7) cancer cell lines. Among all the compounds, 7c, 7d, 7f, and 8f exhibited antiproliferative activities against four tested cell lines with inhibition over 80% at 75 μM after 72 h, whereas, compound 7b and 7g were more selective towards MCF-7 cell line. The IC50 values for compounds 7c, 7d, and 7f were 85.1 μM, 78.7 μM, and 80.6 μM against MCF-7 cell line, respectively, showing slightly higher antiproliferative activtiy than the synthesized and isolated quebecol with an IC50 value of 104.2 μM against MCF-7.

Host-[2]rotaxanes as cellular transport agents

Host-[2]rotaxanes, containing a diarginine-derivatized dibenzo-24-crown-8 (DB24C8) ether as the ring and a cyclophane pocket or an aromatic cleft as one blocking group, are cell transport agents. These hosts strongly associate with a variety of amino acid