5372-40-7 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
[3-(4-CHLOROPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL is used as a building block in the synthesis of other chemical compounds for its potential biological activity. The presence of the chlorophenyl and methanol groups may contribute to its pharmacological properties, making it a candidate for further research and development in the pharmaceutical industry.
Used in Chemical Synthesis:
[3-(4-CHLOROPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL is used as a precursor in the synthesis of various chemical compounds due to its unique structural features. The chlorophenyl and methanol groups can be utilized to create a range of derivatives with different properties and applications, making it valuable in the chemical industry.
Used in Medicinal Chemistry:
[3-(4-CHLOROPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL is used as a scaffold in medicinal chemistry for the development of new drugs. Its structural attributes, including the oxadiazole ring and the attached functional groups, may provide a foundation for designing molecules with specific therapeutic targets and biological activities.
Used in Industrial Applications:
[3-(4-CHLOROPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL is used in various industrial applications due to its chemical properties. [3-(4-CHLOROPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL's stability and reactivity may make it suitable for use in the production of specialty chemicals, materials, or as an intermediate in the synthesis of other valuable compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 5372-40-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5372-40:
(6*5)+(5*3)+(4*7)+(3*2)+(2*4)+(1*0)=87
87 % 10 = 7
So 5372-40-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2O2/c10-7-3-1-6(2-4-7)9-11-8(5-13)14-12-9/h1-4,13H,5H2
5372-40-7Relevant academic research and scientific papers
One-step protection-free synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles as building blocks
Neves Filho, Ricardo A. W.,Da Silva-Alves, Diana C. B.,Dos Anjos, Janaina V.,Srivastava, Rajendra M.
supporting information, p. 2596 - 2602 (2013/07/26)
A simple and straightforward synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles is described. The reaction among arylamidoximes, ethyl glycolate or ethyl lactate, and potassium carbonate in refluxing toluene afforded the desired 1,2,4-oxadiazoles in moderate to good yields. The synthesis has been accomplished in a single step, avoiding protection-deprotection protocols. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.
Cyclic AMP-specific phosphodiesterase inhibitors
-
, (2008/06/13)
Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
