53724-05-3

Upstream product

• 2719-27-9 cyclohexanylcarbonyl chloride 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 54655-07-1 lithium trimethylsilylacetylenide 
• 80783-98-8 N-methoxy-N-methylcyclohexanecarboxamide 
• 133216-88-3 (+/-)-1-cyclohexyl-3-(trimethylsilyl)-2-propynol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 132539-51-6 (3-cyclohexylprop-1-ynyl)trimethylsilane 
• 98-89-5 Cyclohexanecarboxylic acid 

Downstream Products

• 53724-06-4 (3,3-Bis-trimethylsilanyl-1-trimethylsilanyloxy-propa-1,2-dienyl)-cyclohexane 
• 53778-90-8 (3-Trimethylsilanyl-1-trimethylsilanyloxy-prop-2-ynylidene)-cyclohexane 
• 7014-88-2 1-cyclohexyl-3,3-dimethoxypropan-1-one 
• 127618-31-9 (E)-1-cyclohexyl-3-methoxyprop-2-en-1-one 
• 133216-88-3 (R)-1-cyclohexyl-3-(trimethylsilyl)prop-2-yn-1-ol 
• 244191-28-4 trifluoro-methanesulfonic acid 1-cyclohexylidene-3-trimethylsilanyl-prop-2-ynyl ester 
• 950758-23-3 (2-cyclohexyl-1,3-dithiolan-2-ylethynyl)-trimethylsilane 
• 1237786-79-6 (S)-hexa-1,5-dien-3-ylcyclohexane 
• 1378870-78-0 (R)-hex-5-en-1-yn-3-ylcyclohexane 
• 108104-21-8 (S)-1-cyclohexyl-2-propyn-1-ol acetate 
• 53724-07-5 (2,2-Bis-trimethylsilyl-vinyl)-cyclohexylketon 
• 244191-29-5 C₃₂H₄₄Si₂ 
• 105880-38-4 (1S)-1-cyclohexyl-2-propyn-1-ol 
• 950758-19-7 2-cyclohexyl-2-hex-1-ynyl-1,3-dithiolane 

Relevant academic research and scientific papers

Enantioselective Inverse Electron Demand (3 + 2) Cycloaddition of Palladium-Oxyallyl Enabled by a Hydrogen-Bond-Donating Ligand

Cycloaddition reactions between oxyallyl cations and alkenes are important transformations for the construction of ring systems. Although (4 + 3) cycloaddition reactions of oxyallyl cations are well-developed, (3 + 2) cycloadditions remain rare, and an as

A C-H Insertion Approach to Functionalized Cyclopentenones

Cyclopentenones are synthetically versatile structures, and their straightforward construction from alkynone substrates by employing synthetically streamlining C-H insertion is conceptually appealing and of high synthetic potential. But, its implementation is very limited. Herein we report a Au-catalyzed version, which affords 2-bromocyclopent-2-en-1-ones with a broad scope and synthetically desirable diastereoselectivities. The proposed key intermediate capable of the observed insertion into unactivated C-H bonds is a fully functionalized gold vinylidene, which is generated via a novel intermolecular strategy. This flexible access of likely gold vinylidenes opens various opportunities to explore their versatile reactivities.

Mild propargylic oxidation using a diacetoxyiodobenzene/tert-butyl hydroperoxide protocol

A mild propargylic oxidation of alkynes is reported using a diacetoxyiodobenzene/tert-butyl hydroperoxide (DIB/TBHP) protocol. The reactions proceed smoothly at 0 °C and a number of α,β-unsaturated alkynoic ketones are obtained.

Construction of 1,5-enynes by stereospecific Pd-catalyzed allyl-propargyl cross-couplings

The palladium-catalyzed cross-coupling of chiral propargyl acetates and allyl boronates delivers chiral 1,5-enynes with excellent levels of chirality transfer and can be applied across a broad range of substrates.

meso-Phbox-Pd(II) catalyzed tandem carbonylative cyclization of 1-ethynyl-1-propargyl acetate

Palladium(II) catalyzed carbonylation of 1-ethynyl-1-propargyl acetate 1 is described; in the absence of the bisoxazoline (box) ligand, the second triple bond did not react, affording cyclic orthoesters 3 and 4. The use of meso-Phbox-Pd(II) strikingly changed the course of the reaction, yielding bicyclic lactone 2 by tandem carbonylative cyclization as a result of insertion of the second triple bond. The Royal Society of Chemistry.

A convenient synthesis of masked β-ketoaldehydes by the controlled addition of nucleophiles to (trimethylsilyl)ethynyl ketones

The controlled addition of nucleophiles to (trimethylsilyl)ethynyl ketones provides a facile route to β-ketoacetals, β-alkoxy-α,β-unsaturated ketones or vinylogous amides depending on the choice of reaction conditions.