5373-42-2 Usage
Uses
Used in Pharmaceutical Industry:
Thalicarpine is used as an antitumor agent for its significant antitumor activity. It is particularly effective against various types of cancer due to its ability to inhibit tumor growth and progression.
Used in Drug Delivery Systems:
To minimize the adverse effects associated with rapid administration of Thalicarpine, slow intravenous injection is employed. This method ensures that the therapeutic benefits of Thalicarpine are achieved without causing bradycardia, hypotension, and inhibition of respiration in patients.
Used in Research and Development:
Thalicarpine is used as a cytotoxic agent for in vitro studies on HEF and Sa9 cells. This application aids in understanding the mechanisms of action and potential therapeutic applications of Thalicarpine in cancer treatment.
References
Todorov, Damyanova,Dokl. Bolg. Akad. Nauk., 28, 709 (1975)
Check Digit Verification of cas no
The CAS Registry Mumber 5373-42-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5373-42:
(6*5)+(5*3)+(4*7)+(3*3)+(2*4)+(1*2)=92
92 % 10 = 2
So 5373-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C41H48N2O8/c1-42-12-10-23-16-32(44-3)34(46-5)20-27(23)29(42)15-26-19-33(45-4)36(48-7)22-31(26)51-37-18-25-14-30-39-24(11-13-43(30)2)17-38(49-8)41(50-9)40(39)28(25)21-35(37)47-6/h16-22,29-30H,10-15H2,1-9H3/t29-,30-/m0/s1
5373-42-2Relevant academic research and scientific papers
Catalytic Aerobic Cross-Dehydrogenative Coupling of Phenols and Catechols
Xu, Wenbo,Huang, Zheng,Ji, Xiang,Lumb, Jean-Philip
, p. 3800 - 3810 (2019/04/17)
We describe a selective, catalytic aerobic cross-dehydrogenative coupling (CDC) reaction of phenols and catechols that creates aryl ethers. To avoid challenges of selectivity, we employ copper (Cu) coordination to confine substrate redox to the inner coor
Compounds and compositions for treating infection
-
, (2009/04/24)
Compounds from 14 Kenyan plants, including from the root of Dovyalis abyssinica and Clutia robusta have been characterized and isolated, and their uses are disclosed.
Isoquinoline compounds
-
, (2008/06/13)
There is disclosed a novel total synthesis of Thalicarpine which includes inter alia a total synthesis of hernandaline. The novel process is characterized in utilizing simple and readily available starting materials to form a diaryl ether system which is
