53736-75-7

Upstream product

• 3027-05-2 N,N'-diacetylpiperazin-2,5-dione 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 913966-65-1 methyl N-(3-(4-nitrophenyl)pyruvoyl)glycinate 
• 1018337-22-8 methyl N-(2,2-dimethoxy-3-(4-nitrophenyl)propanoyl)glycinate 
• 1018337-19-3 C₁₈H₁₆N₂O₆ 
• 117531-71-2 3-[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-6-[2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-piperazine-2,5-dione 
• 912850-17-0 methyl N-(3-(4-aminophenyl)pyruvoyl)glycinate 

Relevant academic research and scientific papers

Atom-efficient synthesis of 2,6-diazacyclophane compounds through alcoholysis/reduction of 3-nitroarylmethylene-2,5-piperazinediones

Readily available cyclic dehydrodipeptides are convenient starting materials for atom-efficient synthesis of different compounds. A one-pot ring-opening/alcoholysis/hydrolysis process with 3-nitroarylmethylene-2,5-piperazinediones yielded N-3-nitroarylpyr

From cyclic dehydrodipeptides to uncommon acyclic peptide mimetics

1-Acetyl-3-arylmethylene-2,5-piperazinediones gave N-3-arylpyruvylamino esters by acid-promoted alcoholysis under thermal conditions or microwave irradiation. Compounds obtained from 1-acetyl-3-(o-nitro)arylmethylene-2,5-piperazinediones gave, after reduc

Potassium Fluoride on Alumina: Condensation of 1,4-Diacetylpiperazine-2,5-dione with Aldehydes. Dry Condensation under Microwave Irradiation. Synthesis of Albonursin and Analogues

1,4-Diacetylpiperazine-2,5-dione (1) was condensated with aldehydes (2) with KF on alumina without solvent under microwaves or in at room temperature in the presence of DMF.The reaction was stereoselective and some natural products (4a-c) like albonursin (4c) were synthesized.

Conjugated Systems Derived from Piperazine-2,5-dione

The preparation of mono- and of symmetrical and unsymmetrical bis-ylidene derivatives of piperazine-2,5-dione is described.The uv-visible absorption of the products is correlated with acceptor/donor character of the substituents.