53762-46-2Relevant academic research and scientific papers
Discovery of dihydrooxazolo[2,3-: A] isoquinoliniums as highly specific inhibitors of hCE2
Ding, Lixia,Wang, Lu,Zou, Kun,Li, Bo,Song, Yunqing,Zhang, Qihua,Zhao, Yitian,Xu, Zhijian,Ge, Guangbo,Zhao, Bo,Zhu, Weiliang
, p. 35904 - 35912 (2019/11/16)
Human carboxylesterase 2 (hCE2) is one of the most abundant esterases distributed in human small intestine and colon, which participates in the hydrolysis of a variety of ester-bearing drugs and thereby affects the efficacy of these drugs. Herein, a new c
HIV INTEGRASE INHIBITORY OXOISOINDOLINE SULFONAMIDES
-
Page/Page column 72, (2013/03/26)
Novel oxoisoindoline sulfonamide integrase inhibitors are useful to inhibit HIV activity, and are therefore suitable for treatment or prophylaxis of HIV infection, for example in the treatment or prevention of AIDS. In particular embodiments, the inhibito
