537698-34-3Relevant academic research and scientific papers
Diastereoselective addition of terminal alkynes to chiral nitrones: Asymmetric synthesis of propargylic N-hydroxylamines
Patel, Samir K.,Py, Sandrine,Pandya, Shashi U.,Chavant, Pierre Y.,Vallee, Yannick
, p. 525 - 528 (2007/10/03)
1,3-Asymmetric induction in the Et2Zn-catalyzed addition of terminal alkynes was studied with nitrones bearing a chiral auxiliary on their nitrogen atom. The obtained propargylic N-hydroxylamines were generally isolated in good yields and with satisfactory to excellent diastereoselectivities.
