53832-62-5

Upstream product

• 62-53-3 aniline 
• 74-86-2 acetylene 
• 17118-81-9 phosphoric acid diethyl ester 1-methyl-prop-2-ynyl ester 
• 59967-06-5 1-methylprop-2-ynyl methanesulfonate 
• 53487-52-8 1-methylprop-2-ynyl p-toluenesulfonate 
• 602-09-5 1,1'-bi-2-naphthol 
• 7677-24-9 trimethylsilyl cyanide 
• 75-07-0 acetaldehyde 
• 81634-46-0 5,5-dimethyl-1-phenyl-1-aza-5-sila-1-hexen-3-yne 
• 103-70-8 Formanilid 
• 620-71-3 N-(phenyl)-2-methylacetamide 
• 103-84-4 Acetanilid 

Downstream Products

• 93343-55-6 1-morpholino-4-phenylamino-2-pentyne 
• 93343-54-5 1-piperidino-4-phenylamino-2-pentyne 
• 93343-53-4 1-diethylamino-4-phenylamino-2-pentyne 
• 93343-56-7 1-diisopropylamino-4-phenylamino-2-pentyne 
• 99059-78-6 N-(1-methylen-allyl)-aniline 
• 15645-60-0 N-(1-methylallyl)aniline 
• 28128-12-3 (methyl)(phenyl)aminoacetone 

Relevant academic research and scientific papers

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

A rapid and versatile one-pot, 2 × 10 min microwave protocol for the preparation of N-1 and C-6 decorated 3,5-dichloro-2(1H)-pyrazinones was developed. Comparable reaction sequences using classical conditions require about 1-2 days of heating. The α-amino

Intramolecular aromatic substitution and amino-claisen rearrangement in substituted N-(2-propynyl)anilines on electron impact

N-(2-Propynyl)anilines undergo amino-Claisen rearrangement to a minor extent in the ion source, losing a molecule of HCN under electron impact conditions. However, metastable molecular ions with energies closer to threshold undergo Claisen rearrangement g

REACTIONS OF NITROGEN NUCLEOPHILES WITH 1-BROMOALLENES: REGIOSELECTIVE SYNTHESIS OF PROPARGYLAMINES

The results of a study on the reactivity of 3-alkyl- and 3,3-dialkyl-1-bromo-1,2-dienes 2 towards nitrogen nucleophiles, such as aqueous ammonia, lithium amide, aliphatic and aromatic amines allowed us to propose new methods for the synthesis of propargylamines, 1, with an available acetylenic hydrogen.The regio- and the stereoselectivity of these reactions are examined and possible mechanisms are discussed.

Copper(I)-Catalyzed Amination of Propargyl Esters. Selective Synthesis of Propargylamines, 1-Alken-3-ylamines, and (Z)-Allylamines

Copper(I)-catalyzed aminations of propargyl phosphates and acetates proceed under mild reaction conditions to give the corresponding propargylamines which are precursors of 1-alken-3-ylamines and (Z)-allylamines.

SINGLE-STAGE SYNTHESIS OF 3-ARYLAMINO-1-BUTYNES FROM ANILIDES AND ACETYLENE

3-Arylamino-1-butynes were obtained with 20-50percent yields by the reaction of anilides and acetylene (130-160 deg C, initial pressure 12 atm) in the presence of the superbasic system formed during the hydrogenolysis of the anilide by metallic potassium in tetrahydrofuran or dioxane.