538350-91-3Relevant academic research and scientific papers
A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis
Vosburg, David A.,Vanderwal, Christopher D.,Sorensen, Erik J.
, p. 4552 - 4553 (2007/10/03)
An efficient biomimetic synthesis of the reported structure of the hexacyclic, cytotoxic secondary metabolite FR182877 is described. The successful route features the synthesis of a 19-membered ring carbocycle using two π-allyl palladium(II)-mediated C-C
