233256-51-4

Basic information

• Product Name: (3R,4S,6R,6aS,7aS,9aS,10S,11S,12R,12aS,12bS,12cR)-10,12-Dihydroxy-4,6,8,11-tetramethyl-4,6,6a,7,7a,9a,10,11,12,12a,12b,12c-dodecahydro-1H,3H-3,6-etheno-as-indaceno[1,2-d]pyrano[4,3-b]pyran-1-one
• Synonyms: WS-9885B; FR-182877
• CAS NO: 233256-51-4
• Molecular Formula: C₂₄H₃₂O₅
• Molecular Weight: 400.51964
• Mol File: 233256-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4S,6R,6aS,7aS,9aS,10S,11S,12R,12aS,12bS,12cR)-10,12-Dihydroxy-4,6,8,11-tetramethyl-4,6,6a,7,7a,9a,10,11,12,12a,12b,12c-dodecahydro-1H,3H-3,6-etheno-as-indaceno[1,2-d]pyrano[4,3-b]pyran-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S,6R,6aS,7aS,9aS,10S,11S,12R,12aS,12bS,12cR)-10,12-Dihydroxy-4,6,8,11-tetramethyl-4,6,6a,7,7a,9a,10,11,12,12a,12b,12c-dodecahydro-1H,3H-3,6-etheno-as-indaceno[1,2-d]pyrano[4,3-b]pyran-1-one(233256-51-4)
• EPA Substance Registry System: (3R,4S,6R,6aS,7aS,9aS,10S,11S,12R,12aS,12bS,12cR)-10,12-Dihydroxy-4,6,8,11-tetramethyl-4,6,6a,7,7a,9a,10,11,12,12a,12b,12c-dodecahydro-1H,3H-3,6-etheno-as-indaceno[1,2-d]pyrano[4,3-b]pyran-1-one(233256-51-4)

Safety Data

• Hazardous Substances Data: 233256-51-4(Hazardous Substances Data)

Upstream product

• 431900-92-4 (8E,11E,13E,18E)-(4S,5R,15S,16R,17R)-4,8,12,16-Tetramethyl-3-oxo-15,17,20-tris-triethylsilanyloxy-5-trimethylsilanyloxy-icosa-8,11,13,18-tetraenoic acid tert-butyl ester 
• 538350-91-3 (3E,8E,10E,13E)-(5R,6S,7S,17R,18S)-6,10,14,18-Tetramethyl-19-oxo-1-phenylselanyl-5,7-bis-triethylsilanyloxy-17-trimethylsilanyloxy-cyclononadeca-3,8,10,13-tetraenecarboxylic acid tert-butyl ester 
• 431900-89-9 (8E,11E,13E,18E)-(4S,5R,15S,16R,17R)-20-Methoxycarbonyloxy-4,8,12,16-tetramethyl-3-oxo-15,17-bis-triethylsilanyloxy-5-trimethylsilanyloxy-icosa-8,11,13,18-tetraenoic acid tert-butyl ester 
• 431900-91-3 C₄₃H₇₈O₆Si₃ 
• 431900-94-6 (8E,11E,13E,18E)-(4S,5R,15S,16R,17R)-5-Hydroxy-20-methoxycarbonyloxy-4,8,12,16-tetramethyl-3-oxo-15,17-bis-triethylsilanyloxy-icosa-8,11,13,18-tetraenoic acid tert-butyl ester 
• 431900-93-5 (8E,11E,13E,18E)-(4S,5R,15S,16R,17R)-5,20-Dihydroxy-4,8,12,16-tetramethyl-3-oxo-15,17-bis-triethylsilanyloxy-icosa-8,11,13,18-tetraenoic acid tert-butyl ester 
• 393795-04-5 Acetic acid (E)-(6R,7S)-6-hydroxy-7-(methoxy-methyl-carbamoyl)-3-methyl-oct-2-enyl ester 
• 431900-88-8 (6E,9E,11E,16E)-(2S,3R,13S,14R,15R)-2,6,10,14-Tetramethyl-13,15,18-tris-triethylsilanyloxy-3-trimethylsilanyloxy-octadeca-6,9,11,16-tetraenoic acid methoxy-methyl-amide 
• 431900-87-7 Acetic acid (E)-(6R,7S)-7-(methoxy-methyl-carbamoyl)-3-methyl-6-trimethylsilanyloxy-oct-2-enyl ester 

Relevant articles and documents

A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis

An efficient biomimetic synthesis of the reported structure of the hexacyclic, cytotoxic secondary metabolite FR182877 is described. The successful route features the synthesis of a 19-membered ring carbocycle using two π-allyl palladium(II)-mediated C-C