53879-06-4

Basic information

• Product Name: Methanone, (2-azido-5-nitrophenyl)phenyl-
• CAS NO: 53879-06-4
• Molecular Formula: C13H8N4O3
• Molecular Weight: 268.232
• Mol File: 53879-06-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanone, (2-azido-5-nitrophenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-azido-5-nitrophenyl)phenyl-(53879-06-4)
• EPA Substance Registry System: Methanone, (2-azido-5-nitrophenyl)phenyl-(53879-06-4)

Safety Data

• Hazardous Substances Data: 53879-06-4(Hazardous Substances Data)

Upstream product

• 1775-95-7 2-amino-5-nitrobenzophenone 

Downstream Products

• 1228190-98-4 C₁₄H₁₁N₅O₃ 
• 1775-95-7 2-amino-5-nitrobenzophenone 
• 38735-62-5 5-nitro-3-phenyl-2,1-benzisoxazole 

Relevant articles and documents

Microwave-assisted synthesis of 2-aminoquinolines

An improved method for the synthesis of 2-aminoquinolines utilizing microwave-assisted synthesis is described. The process involves rapid microwave irradiation of secondary amines and aldehydes to form enamines followed by the addition of 2-azidobenzophenones with subsequent irradiation to produce the 2-aminoquinoline derivatives. Purification of the products is accomplished in a streamlined manner using solid-phase extraction techniques to produce the desired products in high yields and purity.

Compound and application of compound to treating colon cancer

The invention discloses a compound and application of the compound to treating the colon cancer. The structural formula of the compound is shown in the formula I, wherein R1, R2, R3 and R4 in the formula I are respectively independently chosen from alkyl groups and alkoxy groups, the number of hydrogen atoms, halogen, nitro and carbon atoms in the alkyl group is 1-6, the number of carbon atoms in the alkoxy group is 1-6, R5 is chosen from nitro and -NR6R7, wherein R6 and R7 are respectively independently the hydrogen atom or CH2Ar, the Ar represents a phenyl group or an aryl group, the para-position of the aryl group is substituted by R8, the aryl group is a phenyl group, the R8 is an alkoxy group or the following shown groups, and the number of halogen, hydroxyl and carbon atoms in the R8 is 1-6. The compound also has an obvious effect on inhibiting a tumor sphere from a cancer patient with the colon cancer. In addition, the compound also has an obvious effect on inhibiting the migration and the moving ability of a colon cancer cell line. A novel medicine for treating the colon cancer is expected to be developed on the basis of the compound.

Synthesis of aryl azides via post-cleavage modification of polymer-bound triazenes

Starting from immobilized arenes on the triazene T1 linker resin, cleavage was achieved by trifluoroacetic acid in the presence of trimethylsilyl azide to obtain aryl azides in good yields and excellent purities. A novel cleavage protocol has been introduced and analytical and preparative applications have been presented.