53905-57-0Relevant articles and documents
One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine
Lichman,Lamming,Pesnot,Smith,Hailes,Ward
, p. 852 - 855 (2015)
We describe novel chemoenzymatic routes to (S)-benzylisoquinoline and (S)-tetrahydroprotoberberine alkaloids using the enzymes transaminase (TAm) and norcoclaurine synthase (NCS) in a one-pot, one-substrate 'triangular' cascade. Employment of up to two C-