5393-19-1Relevant articles and documents
Temperature-resistant salt-tolerant anti-swelling clay stabilizer and synthesis method thereof
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Paragraph 0026; 0030; 0031; 0037; 0041; 0042; 0048; 0052, (2019/08/28)
The invention belongs to the technical field of oilfield development, and specifically relates to a temperature-resistant and salt-resistant type anti-swelling clay stabilizer and a synthetic method thereof. The temperature-resistant and salt-resistant type anti-swelling clay stabilizer is prepared through the following steps of enabling phthalic anhydride to react with n-octyl alcohol, thus generating n-octyl phthalic anhydride hemi-ester; carrying out a solution polymerization reaction on the n-octyl phthalic anhydride hemi-ester and 2-(dimethylamino) chloromethane hydrochloride, thus generating an intermediate; finally enabling the intermediate to react with benzyl bromide, thus generating the temperature-resistant and salt-resistant type anti-swelling clay stabilizer, wherein a molar ratio of the phthalic anhydride, the n-octyl alcohol, the 2-(dimethylamino) chloromethane hydrochloride and the benzyl bromide is 1 to 1.1 to 1.3 to 1.6. The temperature-resistant and salt-resistant type anti-swelling clay stabilizer disclosed by the invention has the characteristics that the sources of raw materials are wide, a synthetic technology is simple, the dosage is less, and the oil reservoir adaptability is strong; the temperature-resistant and salt-resistant type anti-swelling clay stabilizer is good in temperature resistance and salt resistance, the temperature resistance can reach 250 DEG C, the mineralization resistance degree can reach 200,000 mg/L, and good compatibility is obtained; the temperature-resistant and salt-resistant type anti-swelling clay stabilizer can be forcefully adsorbed to the surface of clay and is not easy to decompose, long in validity period and high in anti-swelling rate, and the anti-swelling rate can reach 98 percent or more.
Adjuvant and immuno-suppressive effect of six monophthalates in a subcutaneous injection model with BALB/c mice
Larsen, Soren Thor,Hansen, Jitka Stilund,Thygesen, Peter,Begtrup, Mikael,Poulsen, Otto Melchior,Nielsen, Gunnar Damgard
, p. 37 - 51 (2007/10/03)
The prevalence of allergic airway diseases is rapidly increasing in Western Europe and North America. This increase in disease prevalence may be associated with environmental pollutants. The present study investigated the adjuvant and immuno-suppressive effect of a series of monophthalates which are considered to be important metabolites of commonly used phthalate plasticizers. The effects were studied in a screening model. Ovalbumin (OA), used as the model antigen, was injected subcutaneously in the neck region of BALB/cJ mice with or without one of the test substances, mono-n-butyl phthalate (MnBP), monobenzyl phthalate (MBnP), mono-n-octyl phthalate (MnOP), mono-2-ethylhexyl phthalate (MEHP), mono-iso-nonyl phthalate (MiNP) or mono-iso-decyl phthalate (MiDP). The levels of OA-specific IgE, IgG1 and IgG2a in sera were measured by ELISA. Immuno-suppressive effect, defined as a statistically significant reduction in IgE or IgG1 antibody production, was observed with MEHP (1000 μg/ml, IgE and IgG1), MnOP (1000 μg/ml, IgE and IgG1), MiNP (1000 μg/ml, IgE and 10 μg/ml, IgG1) and MiDP (100 μg/ml, IgE and IgG1). Adjuvant effect, defined as a statistically significant increase in IgE or IgG1 antibody level, occurred with MEHP (10 μg/ml, IgE), MnOP (100 μg/ml, and 10 μg/ml, IgG1) and MiNP (100 μg/ml, IgE). No statistically significant immune modulating effect was seen with MBnP and MnBP.
Montmorillonite clay catalysis. Part 10. K-10 and KSF-catalysed acylation of alcohols, phenols, thiols and amines: Scope and limitation
Li, Tong-Shuang,Li, Ai-Xiao
, p. 1913 - 1917 (2007/10/03)
Montmorillonite K-10 and KSF are highly efficient catalysts for the acetylation of a variety of alcohols, thiols, phenols and amines with acetic anhydride. Amino groups can be selectively acetylated in the presence of hydroxy groups, while the hydroxy groups can be preferentially acetylated in the presence of thiol groups. No selectivity is observed between primary and secondary hydroxy groups in the presence of K-10 and KSF. The catalysts are found not to be efficient for acetylation of tertiary alcohols. This method is simple and convenient with minimum environmental impact. The catalysts are also effective for the acylation of alcohols, thiols, phenols and amines with acetyl chloride and benzoyl chloride. Cyclic anhydrides such as succinic anhydride, maleic anhydride and phthalic anhydride and p-toluene sulfonyl chloride show less reactivity than acetic anhydride and acyl chlorides.
