53933-09-8

Basic information

• Product Name: 2-phenylisopropyloxycarbonyl phenyl carbonate
• Synonyms: 2-phenylisopropyloxycarbonyl phenyl carbonate
• CAS NO: 53933-09-8
• Molecular Weight: 256.301
• Mol File: 53933-09-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenylisopropyloxycarbonyl phenyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylisopropyloxycarbonyl phenyl carbonate(53933-09-8)
• EPA Substance Registry System: 2-phenylisopropyloxycarbonyl phenyl carbonate(53933-09-8)

Safety Data

• Hazardous Substances Data: 53933-09-8(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 18597-93-8 cumyl carbazate 
• 133844-03-8 Nα-(2-phenylisopropyloxycarbonyl)-O-(dibenzylphosphono)serylleucine benzyl ester 
• 133844-02-7 Nα-(2-phenylisopropyloxycarbonyl)-O-(dibenzylphosphono)-L-serine 4-nitrobenzyl ester 
• 133844-00-5 Nα-(2-phenylisopropyloxycarbonyl)-O-(dibenzylphosphono)-L-serine 
• 133844-01-6 Nα-(2-phenylisopropyloxycarbonyl)-L-serine 4-nitrobenzyl ester 
• 133844-17-4 Nα-(2-phenylisopropyloxycarbonyl)-L-serine 

Relevant articles and documents

Urotensin II(4-11) Azasulfuryl Peptides: Synthesis and Biological Activity

Cyclic azasulfuryl (As) peptide analogs of the urotensin II (UII, 1, H-Glu-Thr-Pro-Asp-c[Cys-Phe-Trp-Lys-Tyr-Cys]-Val-OH) fragment 4-11 were synthesized to explore the influences of backbone structure on biological activity. N-Aminosulfamides were inserted as surrogates of the Trp7 and Lys8 residues in the biologically relevant Trp-Lys-Tyr triad. A combination of solution- and solid-phase methods were used to prepare novel UII(4-11) analogs 6-11 by routes featuring alkylation of azasulfuryl-glycine tripeptide precursors to install various side chains. The pharmacological profiles of derivatives 6-11 were tested in vitro using a competitive binding assay and ex vivo using a rat aortic ring bioassay. Although the analogs exhibited weak affinity for the urotensin II receptor (UT) without agonistic activity, azasulfuryl-UII(4-11) derivatives 7-9 reduced up to 50% of the effects of UII and urotensin II-related peptide (URP) without affecting their potency.