5394-23-0

Usage

Uses

Used in Analytical Chemistry:
4,7-Dichloro-1,10-phenanthroline is used as a reagent for the determination of metal ions in complex samples. Its chelating properties allow for the accurate measurement and analysis of metal ion concentrations, which is crucial in various analytical processes.
Used in Coordination Chemistry:
In coordination chemistry, 4,7-Dichloro-1,10-phenanthroline is used as a ligand to form stable complexes with metal ions. This application is vital for studying the properties and behaviors of metal complexes, which can provide insights into their potential uses in different fields.
Used in Environmental Applications:
4,7-Dichloro-1,10-phenanthroline is utilized in environmental applications for the detection and removal of metal contaminants. Its ability to form stable complexes with metal ions aids in the efficient extraction and recovery of these contaminants from various environmental matrices.
Used in Pharmaceutical Development:
4,7-Dichloro-1,10-phenanthroline has potential applications in the development of new pharmaceuticals. Its metal-chelating properties can be harnessed to create drugs that target specific metal-dependent biological processes, offering novel therapeutic approaches for various diseases.
Used in Material Science:
In the field of material science, 4,7-Dichloro-1,10-phenanthroline is explored for its potential in creating new materials with unique properties. The stable metal complexes it forms can be incorporated into materials with enhanced characteristics, such as improved catalytic activity or specific optical properties.

InChI:InChI=1/C12H6Cl2N2/c13-9-3-5-15-11-7(9)1-2-8-10(14)4-6-16-12(8)11/h1-6H

Upstream product

• 87330-27-6 1,4,7,10-tetrahydro-1,10-phenanthroline-4,7-dione 
• 3922-40-5 1,10-phenanthroline-4,7-diol 
• 87330-25-4 1,4,7,10-tetrahydro-3,8-bis(ethoxycarbonyl)-1,10-phenanthroline-4,7-dione 
• 87330-26-5 1,4,7,10-tetrahydro-3,8-dicarboxy-1,10-phenanthroline-4,7-dione 
• 4921-71-5 N,N'-bis(2,2-di{ethoxycarbonyl}ethenyl)-1,2-diamino-benzene 
• 95-54-5 1,2-diamino-benzene 
• 503863-91-0 1,2-bis-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidenemethyl)amino]benzene 

Downstream Products

• 92149-07-0 4,7-dimethoxy-1,10-phenanthroline 
• 95943-00-3 4,7-diphenoxy-1,10-phenanthroline 
• 156492-31-8 4,7-bis-(4-methylphenoxy)-1,10-phenanthroline 
• 156492-32-9 4,7-Bis<4-(1,1-dimethylethyl)-phenoxy>-1,10-phenanthroline 
• 156492-33-0 4,7-bis-(4-methoxyphenoxy)-1,10-phenanthroline 
• 111301-95-2 4,7-bis(benzyloxy)-1,10-phenanthroline 
• 168206-33-5 4,7-Bis(4-methylphenylthio)-1,10-phenanthroline 
• 193969-46-9 4,7-bis(p-hydroxyphenoxy)-1,10-phenanthroline 
• 106017-64-5 Cu(C₁₂H₆N₂(Cl)2)(P(C₆H₅)3)2⁽¹⁺⁾*BF₄^(1-)=(Cu(C₁₂H₆N₂(Cl)2)(P(C₆H₅)3)2)BF₄ 
• 1349174-59-9 4,7-bis[4-(trifluoromethyl)phenyl]-1,10-phenanthroline 
• 1233221-54-9 4,7-bis(4-diphenylaminophenyl)-1,10-phenanthroline 
• 1233221-59-4 C₄₈H₃₄N₄ 
• 192226-55-4 4,7-bis(phenylethinyl)-1,10-phenanthroline 
• 676542-82-8 4,7-di(9H-carbazol-9-yl)-1,10-phenanthroline 

Relevant academic research and scientific papers

A novel photosensitizer based on a ruthenium(ii) phenanthroline bis(perylenediimide) dyad: synthesis, generation of singlet oxygen and in vitro photodynamic therapy

In this study, a novel photosensitizer having two perylenediimide units and a phenanthroline ruthenium(ii) coordination moiety (Ru-BP) has been developed for photodynamic therapy (PDT) of cancer cells. This new compound was prepared via reactions of two n

Palladium-Catalyzed Intramolecular Cyclization of Nitroalkenes: Synthesis of Thienopyrroles

In the presence of carbon monoxide, the palladium/phenanthroline system catalyzes the intramolecular amination of thiophene rings following the reduction of a nitroalkene moiety directly attached to the S-heterocyclic ring. Optimization of the ligand and reaction conditions allowed the synthesis of a series of thienopyrroles aryl/alkyl-substituted at either the 2- or 3-position of the pyrrole ring. By using low pressures of carbon monoxide (5 bars), high yields of fused bicyclic compounds have been obtained (up to 98 % yield).

Copper-catalyzed N-arylation of imidazoles and benzimidazoles

(Chemical Equation Presented) 4,7-Dimethoxy-1,10-phenanthroline (L1c) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazoles and benzimidazoles with both aryl iodides and bromides under mild conditions. Further optimization of the system has revealed that the addition of poly(ethylene glycol) accelerates this reaction. A variety of hindered and functionalized imidazoles, benzimidazoles, and aryl halides were transformed in good to excellent yields. Heteroaryl halides were also coupled in moderate to good yields. We also present the results obtained from a series of coupling reactions, which directly compare the use of L1c with other recently reported ligands.

4,7-Dimethoxy-1,10-phenanthroline: An excellent ligand for the Cu-catalyzed N-arylation of imidazoles

4,7-Dimethoxy-1,10-phenanthroline (L) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazole with aryl iodides and bromides under mild conditions. A variety of hindered and functionalized imidazoles and aryl halides were transformed in good to excellent yields.

The synthesis of aromatic diazatricycles from phenylenediamine-bis(methylene Meldrum's acid) derivatives

The thermocyclisation of phenylenediamine-bis(methylene Meldrum's acid) derivatives has been investigated. Those of o-phenylenediamines give 1,10-phenanthroline derivatives, while those of m- and p-phenylenediamines lead to the preferential formation of angular diazatricycles. Thus, for example, the di-Meldrum's acid derivative of 2,5-dichloro-1,4-phenylenediamine gives, via ipso-substitution, the unexpected angular product 19.

The Synthesis of Pyridoquinolines with Dialkylaminopropylamine Side Chains

Several new pyridoquinolines with dimethylaminopropyl side chains including 4,7-bis(3'-dimethylaminopropylamino)-1,10-phenanthroline (1), 4,10-bis(3'-dimethylaminopropylamino)-1,7-phenanthroline (2), 4,10-bis(3'-dimethylaminopropylamino)-6-methyl-1,7-phen