97574-37-3Relevant academic research and scientific papers
Direct C-H Functionalization of Phenanthrolines: Metal- And Light-Free Dicarbamoylations
Demirel, Nemrud,Donkin, Benjamin D. T.,Lee, Ai-Lan,Mooney, David T.,Moore, Peter R.
, p. 17282 - 17293 (2021/12/02)
A direct method for C-H dicarbamoylations of phenanthrolines has been developed, which is capable of directly installing primary, secondary as well as tertiary amides. This is a significant improvement on the previous direct method, which was limited to primary amides. The metal-, light-, and catalyst-free Minisci-type reaction is cheap, operationally simple, and scalable. We demonstrate that the step efficiency toward dicarbamoylated phenanthroline targets can now be significantly improved.
Transition metal-free, visible-light mediated synthesis of 1,10-phenanthroline derived ligand systems
Edwards, Alyn C.,Geist, Andreas,Müllich, Udo,Sharrad, Clint A.,Pritchard, Robin G.,Whitehead, Roger C.,Harwood, Laurence M.
supporting information, p. 8160 - 8163 (2017/07/24)
A broad range of 1,10-phenanthroline substrates was efficiently C-H functionalised, providing rapid, gram-scale access to substituted heteroaromatic cores of broad utility. Furthermore, this C-H functionalisation pathway was extended to the synthesis of previously inaccessible, ultra-soluble, 2,9-bis-triazinyl-1,10-phenanthroline (BTPhen) ligands for advanced nuclear fuel cycles.
