5396-14-5

Basic information

• Product Name: 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER
• Synonyms: 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER;AKOS MSC-0385;Ethyl oxo(2-oxocyclohexyl)acetate;Ethyl 2-oxocyclohexaneglyoxalate;NSC 1175;Oxo(2-oxocyclohexyl)acetic acid ethyl ester
• CAS NO: 5396-14-5
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.22
• Mol File: 5396-14-5.mol
• Article Data: 20

Chemical Properties

• Melting Point: 123-124℃
• Boiling Point: 318.1°Cat760mmHg
• Flash Point: 140°C
• Appearance: /
• Density: 1.161
• Vapor Pressure: 0.000369mmHg at 25°C
• Refractive Index: 1.474
• Storage Temp.: 2-8°C
• PKA: 8.23±0.20(Predicted)
• CAS DataBase Reference: 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER(5396-14-5)
• EPA Substance Registry System: 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER(5396-14-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5396-14-5(Hazardous Substances Data)

Usage

General Description

2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER is a chemical compound that is derived from cyclohexaneglyoxylic acid and ethyl alcohol. It is commonly used as a building block in the synthesis of various pharmaceutical and agrochemical products. 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER is known for its ability to undergo various chemical reactions, such as esterification, alkylation, and oxidation, making it a valuable intermediate in organic synthesis. In addition, it has been studied for its potential biological activities, including its antiviral and antibacterial properties. 2-OXOCYCLOHEXANEGLYOXYLIC ACID ETHYL ESTER is a versatile compound with potential applications in various industries.

InChI:InChI=1/C10H14O4/c1-2-14-10(13)9(12)7-5-3-4-6-8(7)11/h7H,2-6H2,1H3

Upstream product

• 95-92-1 oxalic acid diethyl ester 
• 108-94-1 cyclohexanone 
• 64-17-5 ethanol 
• 771-12-0 α,2-Dioxocyclohexaneacetic Acid 

Downstream Products

• 112744-82-8 1-(3-methoxy-phenyl)-3-(3-methoxy-phenylimino)-1,3,4,5,6,7-hexahydro-indol-2-one 
• 112867-06-8 1-p-tolyl-3-p-tolylimino-1,3,4,5,6,7-hexahydro-indol-2-one 
• 112744-83-9 1-m-tolyl-3-m-tolylimino-1,3,4,5,6,7-hexahydro-indol-2-one 
• 32287-00-6 2-methyl-4,5,6,7-tetrahydro-2H-indazole-3-carboxylic acid 
• 32286-99-0 1-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid 
• 111240-86-9 1-(3-nitro-phenyl)-3-(3-nitro-phenylimino)-1,3,4,5,6,7-hexahydro-indol-2-one 
• 1133-78-4 2-oxo-1,2,5,6,7,8-hexahydro-quinazoline-4-carboxylic acid 
• 113090-44-1 1-(3-chloro-phenyl)-3-(3-chloro-phenylimino)-1,3,4,5,6,7-hexahydro-indol-2-one 
• 111271-52-4 1-phenyl-3-phenylimino-1,3,4,5,6,7-hexahydro-indol-2-one 
• 122389-75-7 1-(4-dimethylamino-phenyl)-3-(4-dimethylamino-phenylimino)-1,3,4,5,6,7-hexahydro-indol-2-one 
• 96274-88-3 1-(3,4-dimethoxy-phenethyl)-3-(3,4-dimethoxy-phenethylimino)-1,3,4,5,6,7-hexahydro-indol-2-one 
• 4492-02-8 ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate 
• 7056-32-8 1-(1-oxo-2-hydroxycyclohexyl)-ethane 
• 90005-77-9 4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxylic acid 

Relevant articles and documents

Indazole hydrazide compound and application thereof

The invention provides an indazole hydrazide compound as shown in a formula (I), wherein R is selected from substituted alkyl, substituted alkenyl or substituted phenyl; substituent groups in the substituted alkyl group and the substituted alkenyl group comprise phenyl and/or substituted phenyl; and R' is selected from H or alkyl. Compared with the prior art, the indole hydrazide compound provided by the invention can be used as an integrin avbeta3 receptor antagonist, has obvious anti-prostatic cancer activity, and has a significant inhibition effect on enzalutamide drug-resistant cell lines.

Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans

The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of

ALKYNYL ALCOHOLS AND METHODS OF USE

The invention relates to compounds of Formula (0): wherein A1-A8, R4 and R5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.