53960-10-4 Usage
Uses
Used in Pharmaceutical Industry:
4-OXO-3,4-DIHYDRO-PHTHALAZINE-1-CARBOXYLIC ACID METHYL ESTER is used as a pharmaceutical candidate for the development of drugs targeting neurological disorders and cardiovascular diseases. Its potential applications in this industry are attributed to its unique chemical structure and properties, which may offer novel therapeutic approaches for these conditions.
Used in Organic Synthesis:
4-OXO-3,4-DIHYDRO-PHTHALAZINE-1-CARBOXYLIC ACID METHYL ESTER is used as a building block in the production of other chemical compounds. Its unique structure and reactivity make it a valuable component in the synthesis of various organic compounds, contributing to the advancement of chemical research and development.
Used in Research and Development:
4-OXO-3,4-DIHYDRO-PHTHALAZINE-1-CARBOXYLIC ACID METHYL ESTER is used as a subject of research to fully understand its properties and potential uses. Further investigation is required to explore its applications in various fields, including pharmaceuticals, organic synthesis, and other industries, to maximize its potential and contribute to scientific progress.
Check Digit Verification of cas no
The CAS Registry Mumber 53960-10-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,6 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 53960-10:
(7*5)+(6*3)+(5*9)+(4*6)+(3*0)+(2*1)+(1*0)=124
124 % 10 = 4
So 53960-10-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O3/c1-15-10(14)8-6-4-2-3-5-7(6)9(13)12-11-8/h2-5H,1H3,(H,12,13)
53960-10-4Relevant academic research and scientific papers
Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans
Mood, Aaron D.,Premachandra, Ilandari Dewage Udara Anulal,Hiew, Stanley,Wang, Fuqiang,Scott, Kevin A.,Oldenhuis, Nathan J.,Liu, Haoping,Van Vranken, David L.
, p. 168 - 173 (2017/03/06)
Four phthalazinones (CIDs 22334057, 22333974, 22334032, 22334012) and one isoquinolone (CID 5224943) were previously shown to be potent enhancers of antifungal activity of fluconazole against Candida albicans. Several even more potent analogues of these compounds were identified, some with EC50 as low as 1 nM, against C. albicans. The compounds exhibited pharmacological synergy (FIC 0.5) with fluconazole. The compounds were also shown to enhance the antifungal activity of isavuconazole, a recently FDA approved azole antifungal. Isoquinolone 15 and phthalazinone 24 were shown to be active against several resistant clinical isolates of C. albicans.
