54013-24-0Relevant articles and documents
Icarisid I type compound, derivatives, pharmaceutical composition and application thereof
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, (2019/03/06)
The invention provides an icarisid I type compound and derivatives, or a stereisomer, geometrical isomer, tautomer, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically-acceptable salt or prodrug of the compound of formula I (shown in the specification). The synthetic materials of the icarisid I type compound and derivatives are selected from quercetin, apigenin, kaempferol, scutellarein, wild scutellarein, chrysin, daidzein, genistein, isorhamnetin, myricetin, luteolin, fisetin or icaritin. By methods of chemical synthesis and bioengineering, the icarisid I type compound and derivatives with better biological effect and higher economic benefit can be synthesized by flavone compounds (such as the apigenin and the quercetin and the like) with higher existence in nature.
